Evidence map›Paper›PMID 40917742›Full record

ArticleTransgender health2025

Postsurgical Pain, Psychosocial Functioning, and Cannabis Use Among Adolescents and Young Adults Undergoing Gender-Affirming Surgery.

Eleanor A J Battison, Emily A Kenyon, Corrin M Murphy, Eline L Lenne, Danielle N Moyer, Sarah W Feldstein Ewing, Anna C Wilson

Abstract read
In one paragraph

Article in Transgender health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eleanor A J BattisonDepartment of Pediatrics, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0001-7037-9325
Emily A KenyonDepartment of Psychology, University of Rhode Island, Providence, Rhode Island, USA.
Corrin M MurphyDepartment of Pediatrics, Oregon Health & Science University, Portland, Oregon, USA.
Eline L LenneSchool of Social Work, Portland State University, Portland, Oregon, USA.
Danielle N MoyerDepartment of Pediatrics, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0001-6335-8120
Sarah W Feldstein EwingDepartment of Psychiatry, University of Connecticut School of Medicine (UConn Health), Farmington, Connecticut, USA.
Anna C WilsonDepartment of Pediatrics, Oregon Health & Science University, Portland, Oregon, USA.

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Oregon Clinical and Translational Research Institute TL1 ProgramTL1TR002371 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLISON Deborah FRYER, JESSINA C MCGREGOR · 2017 to 2026
$6.2M
Risk for opioid abuse and misuse in adolescenceR01DA044778 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI FELDSTEIN EWING, SARAH W., WILSON, ANNA CAMILLE · 2018 to 2022
$3.4M
Adolescent alcohol and cannabis transitions: Associations with multidimensional SES and cannabis policyF31AA031163 · NIAAA · UNIVERSITY OF RHODE ISLAND · PI KENYON, EMILY A · 2024 to 2025
$72k
NCATS NIH HHS TL1 TR002371NCATS NIH HHS UL1 TR002369NIAAA NIH HHS F31 AA031163NIDA NIH HHS R01 DA044778
6 · The paper itself

Abstract

Purpose: Little is known about transgender and gender expansive (TGE) adolescents' and young adults' (AYAs') pain and psychosocial experiences in the acute postsurgical period following gender-affirming surgery (GAS). This study describes pain symptomatology and psychosocial functioning within 1 month after GAS among TGE AYAs, examines immediate postsurgical associations of cannabis use with pain symptomatology, pain catastrophizing, and psychosocial functioning, and explores pain persistence, cannabis use, and psychosocial functioning in a subgroup of individuals 6 months after surgery. Methods: AYAs ( Results: Participants reported acute and persistent pain following GAS. Younger age was associated with improved pain interference in the postoperative stage. Reports of past 30-day cannabis use were high in this sample, and cannabis use was associated with higher pain interference, anxiety, and depression. Conclusion: This study is the first to assess AYA pain functioning, mental health, and cannabis use following GAS within 1 month of surgery and at 6 months. Findings suggest that 6 months after GAS is a postsurgical adjustment phase, necessitating more supportive perioperative and psychosocial resources, including attention to substance use, during this crucial window.

Indexed as

adolescent and young adult (AYA)anxietycannabis usedepressiongender-affirming surgery (GAS)pain

Identifiers

PMID40917742
PMCPMC12411092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.