Evidence map›Paper›PMID 40917676›Full record

ArticleFrontiers in neurology

Analysis of influencing factors and interaction effects on stroke recurrence in patients with middle cerebral artery occlusion treated with mechanical thrombectomy.

Guoliang Li, Zhen Feng, Huiyan Zhang, Yongzhou Zou, Hong Xv, Shunfu Jiang

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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Guoliang LiDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.
Zhen FengDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.
Huiyan ZhangDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.
Yongzhou ZouDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.
Hong XvDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.
Shunfu JiangDepartment of Neurology, Jingdezhen First People's Hospital, Jingdezhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stroke recurrence is an important factor affecting the prognosis of mechanical thrombectomy in patients with middle cerebral artery (MCA) occlusion. This study aims to construct a model for evaluating the degree of stroke recurrence and conduct binary and ternary interaction analysis. Method: We conducted a retrospective analysis of the clinical data of stroke recurrence patients, collecting demographic data, clinical characteristics, treatment factors, and biochemical indicators. Use XGBoost and RF models to screen features that contribute significantly to the degree of recurrence, and evaluate model performance through indicators such as ROC curve, F1 score, accuracy, and recall. Construct a stroke recurrence evaluation model based on the common features selected from these two models. Use the Andersson model to analyze the binary interaction between the model and other factors. Further analyze the three-way interaction between the model and other factors. Result: Both XGBoost and RF models perform well. In the multivariate logistic regression analysis, the recurrence model showed that age, smoking history, and infarct size had a significant impact on the degree of stroke recurrence (OR = 1.006, 1.214, 1.167, all Conclusion: Age, smoking history, and infarct size are important influencing factors on the degree of stroke recurrence in MCA occlusion patients after mechanical thrombectomy treatment. The recurrence model performs differently in different patient populations, and the interaction with age, smoking history, and infarct size is of great significance for evaluating the degree of stroke recurrence.

Indexed as

interaction effectMCA occlusionmechanical bolt removalmiddle cerebral artery occlusionstroke recurrence

Identifiers

PMID40917676
PMCPMC12410075

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