ArticleFrontiers in neurology
Preliminary assessment of age- and sex-related differences in brain volume using Quantib™ brain quantification: a study in a Vietnamese cohort.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Regional Brain Volume Variation Across Adulthood: A Cross-Sectional MRI Analysis of Age, Sex, and Hemispheric Asymmetry.Life (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study evaluates age- and sex-related differences in brain volume, including normalized gray matter (nGM), normalized white matter (nWM), cerebrospinal fluid (CSF) volume, and total intracranial volume (TIV) in cognitively normal adults using automatic volume segmentation on 3.0 Tesla MRI. Methods: A prospective cross-sectional study conducted from October 2021 to September 2022 included 110 cognitively normal participants. They were divided into younger (18-35 years) and older (60-80 years) groups. Brain MRI were performed at Bach Mai Hospital, and volumetric analysis utilized automated segmentation software (Quantib™ Brain, GE Healthcare). Differences in brain volumes were analyzed by age and sex. Results: The younger group comprised 57 participants (30 females, 27 males; mean age 28), and the older group comprised 51 participants (32 females, 19 males; mean age 66). nGM was significantly higher in younger than older groups ( Conclusion: This preliminary study suggests potential age- and sex-related differences in brain volume indices among cognitively normal Vietnamese adults. Additional studies with larger and more representative populations are warranted to confirm and expand upon these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.