Evidence map›Paper›PMID 40917634›Full record

ArticleEvolution, medicine, and public health2025

Survival, resistance, and fitness dynamics of

Sada Boyd-Vorsah, Arturo Torres Ortiz, Sophia Pulido, Brian Bui, Pamela J Yeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evolution, medicine, and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sada Boyd-VorsahDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-2725-2457
Arturo Torres OrtizDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.
Sophia PulidoDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.
Brian BuiDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.
Pamela J YehDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives: Copper is an essential micronutrient and a widely used antimicrobial, yet its widespread application may accelerate microbial resistance. We investigated how long-term copper (II) sulfate (CuSO₄) exposure drives genetic and phenotypic changes in Methodology: Fifty Results: CuSO₄ imposed strong selective pressure, with only 16% of populations surviving prolonged exposure. Survivors exhibited up to eight-fold increases in CuSO₄ resistance, though some reverted to ancestral resistance levels when selective pressure was removed. Fitness assays showed that CuSO₄-selected populations maintained significantly higher fitness in high CuSO₄ environments than controls and ancestors ( Conclusions and implications: CuSO₄ exerts strong and variable selective pressure on

Indexed as

copper stressmetal resistancemicrobial evolutionwhole-genome sequencing

Identifiers

PMID40917634
PMCPMC12409786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.