Evidence map›Paper›PMID 40917623›Full record

SynthesisFrontiers in sports and active living2025

A multilevel meta-analysis of the effects of repeated sprint training in hypoxia on athletic performance.

Meng Han, Binglin Liu

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in sports and active living, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Meng HanThe College of Tianjin Renai, Tianjin, China.
Binglin LiuCollege of Sports Training Science, Tianjin University of Sport, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Repeated-sprint training in hypoxia (RSH) has emerged as a novel strategy to optimize repeated-sprint ability (RSA), aerobic capacity, and anaerobic performance in athletes. Although numerous studies have explored its efficacy compared with repeated-sprint training in normoxia (RSN), inconsistencies remain regarding overall benefits and modulating factors. Objectives: This study aimed to quantify the overall effect of RSH vs. RSN on athletic performance through a systematic review and multilevel meta-analysis and to identify categorical and continuous moderators influencing intervention efficacy. Methods: A comprehensive literature search was conducted across PubMed, Embase, Web of Science, and Cochrane Library up to January 31, 2025. Randomized controlled trials comparing RSH and RSN were included. Two reviewers independently screened, extracted, and assessed study quality. Random-effects multilevel models were used to calculate Hedges' Results: Eighteen studies ( Conclusion: This meta-analysis confirms that RSH provides a moderate performance advantage over RSN, particularly for repeated-sprint ability. Specific implementation parameters such as moderate hypoxia intensity and sufficient training duration enhance efficacy. These findings offer evidence-based guidance for optimizing high-intensity interval training protocols under hypoxic conditions.

Indexed as

aerobic capacityanaerobic powerathletic performancehypoxiameta-analysisrepeated-sprint abilityrepeated-sprint trainingtraining adaptation

Identifiers

PMID40917623
PMCPMC12408497

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.