Evidence map›Paper›PMID 40917420›Full record

ArticleFrontiers in public health2025

Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series analysis.

Matteo Puntoni, Caterina Caminiti, Giuseppe Maglietta, Marcello Lanari, Giacomo Biasucci, Agnese Suppiej, Federico Marchetti, Alessandro De Fanti, Fabio Caramelli, Lorenzo Iughetti and 9 more

Abstract readControlled Clinical TrialMulticenter Study
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Matteo PuntoniClinical and Epidemiological Research Unit, University-Hospital of Parma, Parma, Italy.
Caterina CaminitiClinical and Epidemiological Research Unit, University-Hospital of Parma, Parma, Italy.
Giuseppe MagliettaClinical and Epidemiological Research Unit, University-Hospital of Parma, Parma, Italy.
Marcello LanariPediatric Emergency Unit, IRCCS Azienda Ospedaliera Universitaria di Bologna, Bologna, Italy.
Giacomo BiasucciPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, Piacenza, Italy.
Agnese SuppiejPediatric Clinic, University of Ferrara, Ferrara, Italy.
Federico MarchettiPediatrics and Neonatology Unit, Ravenna Hospital, AUSL Romagna, Ravenna, Italy.
Alessandro De FantiPaediatrics Unit, Santa Maria Nuova Hospital, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
Fabio CaramelliPediatric Intensive Care Unit, IRCCS Azienda Ospedaliera Universitaria di Bologna, Bologna, Italy.
Lorenzo IughettiPediatrics Unit, Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.
Chiara GhizziPaediatrics Unit, Maggiore Hospital, Bologna, Italy.
Enrico VallettaPediatric Unit, G.B. Morgagni-L. Pierantoni Hospital, AUSL Romagna, Forlì, Italy.
Gianluca VerginePediatric Clinic, Rimini Hospital, AUSL Romagna, Rimini, Italy.
Marcello StellaPediatric Unit, AUSL Romagna, Cesena, Italy.
Beatrice CampanaDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Valentina FainardiDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Michela DeolmiPediatric Clinic, University-Hospital of Parma, Parma, Italy.
Susanna EspositoDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Emilia-Romagna Paediatric COVID-19 Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Evidence exists on the major disruptions in pediatric healthcare services occurred during the COVID-19 pandemic, but what happened when all restrictions were lifted is unclear. This study examined trends in pediatric hospital admission and Emergency Department visit rates during the first 12 months following the end of the state of emergency in Italy, compared to pre-pandemic levels. Methods: We conducted a multicenter, retrospective, quasi-experimental before after study including 11 North Italian hospitals. Using electronic health records from March 2017 to March 2023, we compared standardized rates recorded during 1 year following the end of the emergency with the situation before the pandemic, using interrupted time series. We examined trends overall and for individual diagnostic categories that had exhibited the largest impact in our previous studies concerning data up to March 2022. Results: A total of 104,083 hospitalizations and 858,762 Pediatric Emergency Department visits were analyzed. Compared to the 3 years before the outbreak, post-emergency hospitalization rates increased by 23% (Standardized Hospitalization Rate Ratio 1.23, 95% CI 1.20-1.25), whereas Pediatric Emergency Department visits after a sharp decrease returned to pre-pandemic rates (Standardized Incidence Rate Ratio 0.98, 95% CI 0.96-1.00). Mental health-related hospitalizations exhibited the largest increase, peaking in the first months of the post-pandemic year (level change, Hospitalization Rate Ratio (HRR)2.57, 95%CI 1.61-4.12), then decreasing slightly in the last months but still maintaining much higher than pre-pandemic values. Notably, hospitalization rates in adolescent girls (12-17 years) increased almost 4-fold (level change, HRR 3.72, 95%CI 2.02-6.85, Conclusion: The COVID-19 pandemic has had long-term consequences on pediatric healthcare utilization. Data from this and future studies can guide the development of proactive policies aiming to mitigate healthcare disruptions and ensure access to essential pediatric services in the event of future health crises, with special consideration to vulnerable populations. The persistent rise in hospital admissions for mental health disorders, particularly teenage girls, make this field a challenging, absolute priority for public health.

Indexed as

COVID-19Emergency Service, HospitalHospitalizationPatient Acceptance of Health CareAdolescentChildChild, PreschoolFemaleHumansInfantInterrupted Time Series AnalysisItalyMalePandemicsRetrospective StudiesSARS-CoV-2healthcare service utilizationinterrupted time series regression analysismental disorderspediatric emergency departmentpediatric hospitalizationspost-emergencypost-pandemic effectsquasi-experimental design

Identifiers

PMID40917420
PMCPMC12408626

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.