Evidence map›Paper›PMID 40917347›Full record

ArticleFrontiers in endocrinology2025

Sequential treatment for diabetic foot ulcers in aortic dissection patients: a case report.

Huan Liang, Pin Deng, Lili Yang, Yusong Yuan, Xiaofang Ding

Abstract readCase Reports
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huan Liang *Beijing Longfu Hospital, Beijing, China.
Pin Deng *Institute of Basic Theory of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Lili YangBeijing Longfu Hospital, Beijing, China.
Yusong YuanDepartment of Trauma and Orthopaedics, China-Japan Friendship Hospital, Beijing, China.
Xiaofang DingDepartment of Orthopedics, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic foot ulcers (DFUs) represent a prevalent complication of diabetes, with a lifetime risk ranging from 15% to 25% among diabetic patients. Research indicates that anticoagulation plays a crucial role in the management of newly diagnosed cases of diabetic lower extremity atherosclerotic obliterative disease. However, in the present case, the patient developed dry gangrene in both toes after receiving vasodilator drugs during an emergency intervention for sudden aortic dissection. Given that traditional treatments, such as anticoagulation and transfemoral amputation, may not be appropriate for every case, it is imperative to explore alternative therapeutic options. This case report presents pioneering clinical evidence of a tri-therapeutic strategy integrating biomechanical conditioning transverse tibial bone transport (TTBT), Traditional Chinese Medicine Compress Therapy (TCM-CT), and antibiotic-loaded bone cement (ALBC) for diabetic foot ulcer regeneration. This innovative paradigm demonstrates concurrent activation of mechanobiological signaling pathways, phytochemical bioactivity, and sustained antimicrobial protection, achieving complete epithelialization in refractory neuropathic wounds.

Indexed as

Aortic DissectionDiabetic FootAgedAnti-Bacterial AgentsHumansMaleMedicine, Chinese TraditionalMiddle AgedAnti-Bacterial Agentsantibiotic-loaded bone cement (ALBC)aortic dissection (AD)case reportdiabetic foot ulcer (DFU)transverse tibial bone transport

Identifiers

PMID40917347
PMCPMC12408281

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.