ArticleTurkish journal of biology = Turk biyoloji dergisi2025
Lactic acid bacteria alleviate neuronal excitotoxicity and extend
Article in Turkish journal of biology = Turk biyoloji dergisi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: Neuronal cell death plays a critical role in the development of neurological disorders associated with aging. This study aimed to evaluate the beneficial effects of heat-ki lled lactic acid bacteria (hkLAB) on neuroblastoma cells and Materials and methods: We pretreated heat-killed Results: Our findings indicate that hkCNU395 and hkCNU396 protected against glutamate-induced cell death via modulation of the Bax/Bcl-2 apoptosis regulator ratio and enhancement of endogenous antioxidant enzyme activity. Moreover, hkCNU396 significantly improves survival rates in Conclusion: These results highlight hkCNU396 as a promising paraprobiotic candidate for patients suffering from degenerative neurodegenerative diseases.
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