Evidence map›Paper›PMID 40917184›Full record

ArticleHeart rhythm O22025

Trends in cardiac conduction disorder-associated mortality among young adults in the United States, 2010-2020.

Marco Zuin, Cristina Balla, Pugazhendhi Vijayaraman, Francesco Vitali, Matteo Bertini

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco ZuinCardiology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Cristina BallaCardiology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Pugazhendhi VijayaramanGeisinger Heart Institute, Wilkes Barre, Pennsylvania.
Francesco VitaliCardiology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Matteo BertiniCardiology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac Conduction Disorders (CCDs) in young adults aged 25-44 years represent an important and poorly investigated condition associated with death. Objective: We assessed trends in CCD-associated mortality in the United States (US) from 2010 to 2020 among young adults to determine differences by sex, ethno-racial groups, urbanization, census region, and underlying causes of death. Methods: Mortality data were obtained from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database, covering the period from 2010 to 2020. Age-adjusted mortality rates (AAMRs) were analyzed using joinpoint regression modeling and presented as the estimated average annual percentage change (AAPC), along with corresponding 95% confidence intervals (95% CIs). Results: In the US, between 2010 and 2020, 4312 US young adults aged between 25 and 44 years died from CCD, equating to a rate of 10.9 deaths per 1000 population. The relative AAMR increased with a seemingly exponential distribution (AAPC: +10.7%; 95% CI: 9.1-12.3; Conclusion: CCD-associated mortality among young adults has increased over the last decade in the US, with notable racial and regional disparities.

Indexed as

Cardiac Conduction DisordersEthnicityMortalityRaceTrend

Identifiers

PMID40917184
PMCPMC12411946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.