ArticleHeart rhythm O22025
Diagnostic performance of the fragmented QRS complex on electrocardiogram for detecting myocardial scars assessed by 3.0 Tesla cardiac magnetic resonance imaging.
Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Fragmented QRS on Baseline Electrocardiography Predicts Anatomically Significant Stenosis in Patients With Intermediate Coronary Lesions on Coronary Computed Tomography Angiography.Cardiology research · 2026Article
- Premature Ventricular Contractions as a Result of Subacute Myocarditis in a Professional Football Player.JACC. Case reports · 2026Article
- Preoperative fragmented QRS as a predictor of postoperative left ventricular systolic dysfunction after isolated mitral valve replacement.BMC cardiovascular disorders · 2026Article
- Resynchronisation efficacy of pacing strategies depends on the assessment metric: a computational study.Frontiers in physiology · 2026Article
- Predicting major adverse cardiovascular events during hospitalization in patients with acute myocardial infarction after percutaneous coronary intervention: Development and validation of a nomogram.Pakistan journal of medical sciences · 2025Article
- The utility of fragmented QRS in association with strain echocardiography in predicting significant coronary artery stenosis.Journal of cardiovascular and thoracic research · 2024Article
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Authors and funding
5 authors.
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Abstract
Background: Fragmented QRS complex (f-QRS) on a 12-lead electrocardiogram (ECG) has been associated with myocardial scars. However, its diagnostic accuracy for detecting myocardial scars assessed by cardiac magnetic resonance (CMR) imaging remains uncertain. Objective: To evaluate the diagnostic performance of f-QRS for detecting myocardial scars assessed by 3.0 CMR. Methods: Patients who underwent 3.0 Tesla CMR between May 2020 and May 2023 were included. A 12-lead ECG was assessed for f-QRS, defined as the presence of an R' wave or notching in the nadir of the S wave in at least 2 contiguous leads. The diagnostic performance of f-QRS in detecting myocardial scars in corresponding left ventricular segments was analyzed. Results: Overall, 1692 patients were included. f-QRS presented in 826 (49%) participants which were more prevalent in men (59.4% vs 46.0%), those with a history of coronary artery disease (26.4% vs 20.6%), and those with myocardial scars (48.9% vs 37.3). The sensitivity and specificity of f-QRS from ECG were 25.6% and 88.7% for anterior; 22.1% and 91.5%, for lateral; and 42.9% and 63.4% for inferior segments. Conclusion: f-QRS demonstrates high specificity for detecting myocardial scars on CMR, though its sensitivity is limited.
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