Evidence map›Paper›PMID 40917091›Full record

ArticleFrontiers in nutrition2025

Case Report: Reversible chorea arising from severe vitamin B12 deficiency due to autoimmune gastritis: a comprehensive case study.

Meifang Yang, Yifan Geng, Zhiren Chen, Zixuan Zhou, Wenjuan Huang, Weiwei Chen, Xia Zhang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Meifang Yang *Department of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.
Yifan Geng *Department of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.
Zhiren Chen *Department of Neurology, Xuzhou Clinical College, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Zixuan ZhouDepartment of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.
Wenjuan HuangDepartment of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.
Weiwei Chen *Department of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.
Xia Zhang *Department of Neurology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment, ocular neuropathy, sensorimotor polyneuropathy, and subacute combined spinal cord degeneration can all result from a common illness called vitamin B12 insufficiency. With regard to extrapyramidal movement disorders, it is rare, frequently misdiagnosed, and under recognized, which postpones timely treatment. A case study of a 66-year-old man with acute-onset and reversible choreoathetoid symptoms is presented in this publication. A significant vitamin B12 deficiency and an abnormal hypermetabolism in the basal ganglia region were detected by 18F-FDG PET/CT. Remarkably, the patient's dyskinesia disappeared as soon as vitamin B12 replacement therapy was administered. The patient's etiology was identified as a mix of vitamin B12 malabsorption and inadequate intake from autoimmune-related gastritis. In order to achieve the best potential therapeutic results, this case highlights the importance of timely and correct diagnosis, timely treatment of vitamin B12 deficiency based on its underlying etiology, and careful research of multiple etiologies.

Indexed as

18F-FDG PET/CTautoimmune gastritischoreamovement disordersvitamin B12 deficiency

Identifiers

PMID40917091
PMCPMC12408260

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