Evidence map›Paper›PMID 40917079›Full record

ArticleInternational journal of cardiology. Cardiovascular risk and prevention2025

Electrocardiogram markers predicting ischemic stroke after acute coronary syndrome.

Matilda Hurskainen, Juho Tynkkynen, Leo-Pekka Lyytikäinen, Terho Lehtimäki, Kjell Nikus, Jussi Hernesniemi

Abstract read
In one paragraph

Article in International journal of cardiology. Cardiovascular risk and prevention, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matilda HurskainenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Juho TynkkynenCentre of Vascular Surgery and Interventional Radiology, Tampere University Hospital, Tampere, Finland.
Leo-Pekka LyytikäinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Terho LehtimäkiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Kjell NikusFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jussi HernesniemiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with coronary artery disease (CAD) have increased risk of ischemic stroke (IS). Our aim was to screen for significant electrocardiogram (ECG) features for IS risk in patients treated for acute coronary syndrome (ACS). Methods: This retrospective registry study is based on 7760 ACS patients treated in Tays Heart Hospital (2007-2018) with follow-up for incident IS until December 31st Results: From 7760 patients, 489 (6.3 %) suffered IS during a median follow-up of 5.7 years (IQR 3.1-8.8). In the final multivariable model, the main risk factors were premature ventricular complexes (PVCs) or aberrantly conducted complexes in AF/AFL (SDH, 2.01 [1.22-3.31]), left ventricular (LV) hypertrophy (LVH) by Sokolow-Lyon criteria (SDH, 1.52 [1.12-2.06]), S wave amplitude in lead V4 (SDH, 1.13 [1.05-1.21]) and negative P wave peak time in lead V2 (SDH, 1.12 [1.02-1.23]). T wave amplitude in lead V6 (SDH, 0.78 [0.69-0.88]) and T wave duration in lead aVL (SDH, 0.85 [0.78-0.92]) showed an inverse association with IS risk. The continuous variables correspond to 1 SD. Conclusions: ECG markers demonstrating LV dysfunction, LVH and atriopathy associate with IS risk after ACS, although external validation is still required.

Indexed as

Acute coronary syndromeECGIschemic strokeMyocardial infarctionRisk factors

Identifiers

PMID40917079
PMCPMC12410464

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.