Evidence map›Paper›PMID 40916882›Full record

ArticleJournal of pathology and translational medicine2025

Composite chronic lymphocytic leukemia and mantle cell lymphoma involving the bone marrow: a case report and literature review.

Roksolana Demianets, Susan O'Brien, Khosrow Mahdavi, Chenchen Niu, Sumayya Aslam, Truc Tran, Ying Zhang, Ashley Gamayo, Xiaohui Zhao, Sherif A Rezk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pathology and translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roksolana DemianetsDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Susan O'BrienDepartment of Hematology and Oncology, University of California, Irvine (UCI), Irvine, CA, USA.
Khosrow MahdaviDepartment of Hematology and Oncology, University of California, Irvine (UCI), Irvine, CA, USA.
Chenchen NiuDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Sumayya AslamDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Truc TranDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Ying ZhangDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Ashley GamayoDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Xiaohui ZhaoDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.
Sherif A RezkDepartment of Pathology and Laboratory Medicine, University of California, Irvine (UCI), Irvine, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a clinically indolent lymphoproliferative disorder characterized by accumulation of mature B-cell lymphocytes. Given the common CD5 co-expression, mantle cell lymphoma (MCL) is one of the most important entities in the differential diagnosis. MCL and CLL/SLL might exhibit overlapping morphologic and immunohistochemical features, making diagnosis particularly difficult in cases of composite lymphomas. Here, we present a unique case of composite lymphoma in an 86-year-old male, along with a literature review on the immunophenotypic variability of both MCL and CLL, which should always be confirmed with additional ancillary cytogenetic and molecular studies.

Indexed as

Chronic lymphocytic leukemiaComposite lymphomaCyclin D1Mantle cell lymphomaSOX11

Identifiers

PMID40916882
PMCPMC12455405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.