Evidence map›Paper›PMID 40916821›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2025

Lingyu Wei, Shu Tong, Meng'er Wang, Hongzheng Ren, Jinsheng Wang

Abstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lingyu WeiClinical Research Center Laboratory, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000. weilingyu0425@163.com.
Shu TongDepartment of Pathology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000.
Meng'er WangDepartment of Pathology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000.
Hongzheng RenDepartment of Pathology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000.
Jinsheng WangDepartment of Pathology, First Clinical College, Changzhi Medical College, Changzhi 046000. wjsczmc@163.com.

Funding

the Faculty Research Fund of Heping Hospital Affiliated to Changzhi Medical College HPYJ202216
6 · The paper itself

Abstract

objectivesAcute lung injury (ALI) is an acute respiratory failure syndrome characterized by impaired gas exchange. Due to the lack of effective targeted drugs, it is associated with high mortality and poor prognosis.

methodsEighteen specific pathogen-free (SPF) C57BL/6 mice were randomly divided into normal control (NC; intranasal saline), lipopolysaccharide (LPS; 5 mg/kg intranasally to induce ALI), and LPS+TW (50 mg/kg TW by gavage on the first day of modeling, followed by 5 mg/kg LPS intranasally to induce ALI) groups (

resultsCompared with the NC group, the LPS group showed marked lung pathology with significantly increased histopathological scores and wet-to-dry ratios (both

conclusionsTW alleviates the progression of LPS-induced ALI in mice, potentially by reducing the proportion of MDSCs in lung tissues and attenuating the immunosuppressive function of PMN-MDSCs.

Indexed as

Acute Lung InjuryCell DifferentiationMyeloid-Derived Suppressor CellsTripterygiumAnimalsCytokinesDiterpenesEpoxy CompoundsLipopolysaccharidesMaleMiceMice, Inbred C57BLNitric Oxide Synthase Type IIPhenanthrenesReactive Oxygen SpeciesCytokinesDiterpenesEpoxy CompoundsLipopolysaccharidesNitric Oxide Synthase Type IIPhenanthrenesReactive Oxygen Speciestriptolideacute lung injuryarginase-1myeloid-derived suppressor cellsreactive oxygen speciesTripterygium wilfordii

Identifiers

PMID40916821
PMCPMC12406111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.