Evidence map›Paper›PMID 40916542›Full record

Observational studyAnnals of medicine2025

Clinical value of preoperative serum calcium level in predicting deep infiltrative endometriosis among ovarian endometrioma.

Huiyun Jiang, Yingxiang Wang, Jie Ding, Yu Zhang

Abstract readObservational Study
In one paragraph

Observational study in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huiyun JiangDepartment of Gynecology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Yingxiang WangDepartment of Gynecology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Jie DingDepartment of Gynecology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.
Yu ZhangDepartment of Gynecology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate preoperative serum calcium levels and their association with deep infiltrating endometriosis (DIE) in ovarian endometrioma.

designA retrospective, observational cohort study.

participantsA total of 2,557 women who underwent surgery for benign ovarian tumors were initially enrolled. Of these, 987 were pathologically confirmed to have endometriosis, while the remaining 1570 did not.

resultEndometriosis (EM) group had significantly lower albumin-adjusted calcium levels than the non-EMs group (

conclusionAlbumin-adjusted calcium level was lower in patients diagnosed with EM compared to those with other benign ovarian tumors. The combined use of albumin-adjusted calcium and CA125 may potentially offer enhanced diagnostic utility for EM, though further validation is required. Moreover, a lower serum level of albumin-adjusted calcium was associated with the presence of DIE among EM patients.

Indexed as

CalciumEndometriosisOvarian DiseasesOvarian NeoplasmsAdultCA-125 AntigenFemaleHumansMiddle AgedPreoperative PeriodRetrospective StudiesYoung AdultCA-125 AntigenCalciumdeep infiltrating endometriosisEndometriosislogistic regressionserum calcium

Identifiers

PMID40916542
PMCPMC12418798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.