Evidence map›Paper›PMID 40916536›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2025

[β-sitosterol, an important component in the fruits of

Junyi Li, Siyuan Chen, Liyao Xie, Jin Wang, Ao Cheng, Shaowei Zhang, Jiyu Lin, Zhihan Fang, Yirui Pan, Chonghe Cui and 3 more

Abstract readEnglish Abstract
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Junyi LiFirst School of Clinical Medicine.
Siyuan ChenDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Southern Medical University; Guangdong Provincial Key Laboratory of Single Cell Technology and Application, Guangzhou 510000, China.
Liyao XieFirst School of Clinical Medicine.
Jin WangSecond School of Clinical Medicine, Southern Medical University, Guangzhou 510000, China.
Ao ChengFirst School of Clinical Medicine.
Shaowei ZhangFirst School of Clinical Medicine.
Jiyu LinSecond School of Clinical Medicine, Southern Medical University, Guangzhou 510000, China.
Zhihan FangSecond School of Clinical Medicine, Southern Medical University, Guangzhou 510000, China.
Yirui PanSecond School of Clinical Medicine, Southern Medical University, Guangzhou 510000, China.
Chonghe CuiSchool of Health, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Gengxin ChenSchool of Health, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Chao ZhangSecond School of Clinical Medicine, Southern Medical University, Guangzhou 510000, China.
Li LiDepartment of Pathogenic Biology & Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University. Haikou 571199, China.

Funding

National Natural Science Foundation of China 82473569
6 · The paper itself

Abstract

objectivesTo elucidate the anti-aging effect of β-sitosterol (BS), an important component in the fruits of

methods

resultsBoth BS treatment and ETS-5 knockdown significantly prolonged the lifespan, promoted lipid accumulation and reduced lipid peroxidation in

conclusionsBS inhibits ferroptosis in

Indexed as

AlpiniaCaenorhabditis elegansFerroptosisLongevitySitosterolsAnimalsFruitHumansgamma-sitosterolSitosterolsETS-5ferroptosissenescenceβ-sitosterol

Identifiers

PMID40916536
PMCPMC12415562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.