SynthesisCroatian medical journal2025
The effect of sleep-oriented non-pharmacological interventions in preventing delirium: a systematic review of randomized controlled trials.
Synthesis in Croatian medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo systematically review randomized controlled trials evaluating the efficacy of sleep-oriented non-pharmacological interventions for delirium prevention in intensive care units.
methodsWe searched PubMed, Web of Science, Scopus, and the Cochrane Library for randomized controlled trials evaluating the efficacy of sleep-oriented, non-pharmacological interventions for delirium prevention in intensive care units published in English between 2019 and 2024. The methodological quality of the included studies was independently evaluated by two researchers using the Joanna Briggs Institute tool.
resultsThis review included eight randomized controlled trials (n = 649). Six studies assessed the effect of earplugs and masks on delirium prevention in intensive care patients. Three studies indicated that earplugs and eye masks effectively prevented delirium, while three studies found no effect. One study assessed the use of earplugs and masks as part of a bundle of interventions and reported a positive effect. Four studies showed an effect on sleep. None of the sleep-oriented non-pharmacological interventions assessed in these studies reported any harmful effects.
conclusionAlthough several high-quality studies showed that these interventions significantly lowered delirium incidence, some trials found no effect, highlighting variability in outcomes.
Indexed as
Identifiers
40916505PMC12426865What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.