Evidence map›Paper›PMID 40916459›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

In-Hospital Outcomes of Simultaneous and Staged Transcatheter Aortic Valve Replacement and Endovascular Aneurysm Repair.

Alex Pu, Rahul V Annabathula, Haytham Allaham, Diljon Chahal, Shahab Toursavadkohi, Anuj Gupta

Abstract readComparative Study
PubMed Full text at PMC Publisher
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Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

  1. Article
  2. Article
  3. In-Hospital Outcomes of Simultaneous and Staged Transcatheter Aortic Valve Replacement and Endovascular Aneurysm Repair.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
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5 · Who and what money

Authors and funding

6 authors.

Alex PuDepartment of Internal Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7829-9845
Rahul V AnnabathulaDivision of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Haytham AllahamDivision of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Diljon ChahalDivision of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Shahab ToursavadkohiDivision of Vascular Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Anuj GuptaDivision of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

introductionPatients with aortic aneurysms are at elevated risk of rupture, dissection and death during and after transcatheter aortic valve repair (TAVR), often requiring consideration for endovascular aneurysm repair (EVAR) at the time of TAVR. However, data comparing outcomes of simultaneous versus staged TAVR-EVAR are limited.

methodsUsing the National Inpatient Sample between the years 2018 and 2021, we compared in-hospital outcomes of simultaneous and staged TAVR-EVAR. Patients who underwent both TAVR and EVAR during hospital admission were identified with International Classification of Diseases 10th Revision procedure codes. Patients were stratified by simultaneous (defined as same day) versus staged (defined as different day) procedures. Propensity score matching was done in a 2:1 fashion to account for differences in baseline characteristics, and mixed effects multivariate regression models were used to assess differences in in-hospital mortality, cost of hospitalization, length of stay, and other procedural complications.

resultsA total of 270 patients underwent simultaneous TAVR-EVAR, while a total of 70 underwent staged TAVR-EVAR. After propensity score matching, 98 patients undergoing simultaneous TAVR-EVAR were matched to 49 patients undergoing staged TAVR-EVAR. No significant differences in baseline characteristics were observed after matching. In-hospital mortality between the matched groups was not significantly different (OR 0.67, p = 0.409), however the simultaneous group was associated with shorter length of stay (3 [2.0-11.75] days vs. 14 [13.0-17.0] days, p < 0.001) and less total hospital costs ($77,691 [$65,153-$103,854] vs. $148,617 [$128,339-$217,988]; p < 0.001). The matched simultaneous group was also associated with lower incidence of acute kidney injury (25.5% vs. 65.3%; OR 0.11, p < 0.001), blood transfusions (20.4% vs. 40.8%; OR 0.37, p = 0.01), and access site complications (< 10.2% vs. 49.0%; OR 0.00, p < 0.001).

conclusionSimultaneous TAVR-EVAR is associated with fewer adverse complications and lower cost of hospitalization without increased in-hospital mortality, suggesting it is more cost effective than staged TAVR-EVAR during the same hospital admission.

Indexed as

Aortic AneurysmAortic Valve StenosisBlood Vessel Prosthesis ImplantationEndovascular ProceduresTranscatheter Aortic Valve ReplacementAgedAged, 80 and overDatabases, FactualEndovascular Aneurysm RepairFemaleHospital CostsHospital MortalityHumansLength of StayMalePostoperative Complicationsaortic aneurysmaortic stenosisendovascular aneurysm repairtranscatheter aortic valve repair

Identifiers

PMID40916459
PMCPMC12584566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.