Evidence map›Paper›PMID 40916375›Full record

ArticleRenal failure2025

Transition to a combination of peritoneal dialysis and hemodialysis in chronic kidney disease patients receiving peritoneal dialysis treatment: a single-center study.

Mehmet Usta, Nur Ozer Sensoy, Hatice Ortac, Alparslan Ersoy

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mehmet UstaDepartment of Nephrology, University of Health Sciences, Bursa City Training and Research Hospital, Bursa, Turkey.ORCID 0000-0002-6879-7744
Nur Ozer SensoyDepartment of Nephrology, University of Health Sciences, Bursa City Training and Research Hospital, Bursa, Turkey.ORCID 0000-0001-8809-2250
Hatice OrtacInstitute of Health Sciences, Department of Biostatistics, Uludağ University, Bursa, Turkey.ORCID 0000-0002-1199-1706
Alparslan ErsoyDivision of Nephrology, Department of Internal Medicine, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.ORCID 0000-0002-0710-0923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal dialysis (PD) and hemodialysis (HD) are the two primary renal replacement therapies for patients with end-stage renal disease (ESRD). While PD is an effective and convenient modality, long-term use can lead to ultrafiltration failure, recurrent peritonitis, and progressive structural alterations in the peritoneal membrane, necessitating a transition to HD. In recent years, rather than a complete transition, the combined use of PD and HD has emerged as a viable alternative, offering potential advantages for selected patient populations.This retrospective study included patients with PD-related complications, such as resistant hypervolemia, frequent peritonitis episodes, peritoneal failure, and clinical deterioration. Based on eligibility criteria, patients were either transitioned to HD or initiated on combined PD+HD therapy. A total of 28 patients underwent transition to HD, while 26 received PD+HD combination therapy. Survival rates, Kt/V, residual urine output, and various laboratory parameters were evaluated and compared between the two groups. Both groups demonstrated significant improvements in Kt/V, volume stabilization, and cardiovascular stability after transitioning from PD. However, no statistically significant differences were observed in laboratory parameters between the two groups. These findings suggest that for patients experiencing PD failure, frequent peritonitis, or fluid overload, combined PD+HD therapy may serve as a feasible alternative to conventional HD. Careful patient selection and individualized treatment planning are crucial for optimizing outcomes. Given its comparable efficacy to HD, combined PD+HD therapy may represent an important option for patients requiring a tailored approach to dialysis.

Indexed as

Kidney Failure, ChronicPeritoneal DialysisRenal DialysisAdultAgedFemaleHumansMaleMiddle AgedPeritonitisRetrospective StudiesSurvival RateTreatment Outcomechronic kidney diseasecombined dialysis therapyhemodialysisPeritoneal dialysistransition from peritoneal dialysis to hemodialysis

Identifiers

PMID40916375
PMCPMC12418792

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.