Interactions Between Active Matters and Endogenous Fields.

Jinwei Lin, Qiaoxin Guan, Jiangqi Feng, Shuqin Chen, Leilei Xu, Jianguo Guan, Samuel Sánchez

Abstract readReview

In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Interactions Between Active Matters and Endogenous Fields.Advanced materials (Deerfield Beach, Fla.) · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinwei LinInstitute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Carrer de Baldiri i Reixac, 10-12, Barcelona, 08028, Spain.

Qiaoxin GuanState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China.

Jiangqi FengDepartment of Chemistry and Institute for the Physics of Living Systems, University College London, London, WC1H 0AJ, UK.

Shuqin ChenInstitute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Carrer de Baldiri i Reixac, 10-12, Barcelona, 08028, Spain.

Leilei XuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China.

Jianguo GuanState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China.

Samuel SánchezInstitute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Carrer de Baldiri i Reixac, 10-12, Barcelona, 08028, Spain.ORCID 0000-0002-5845-8941

Funding

Agencia Estatal de Investigación CEX2018-000789-SCentro de Excelencia Severo OchoaChina Scholarship CouncilCultivation Program of Wuhan Institute of Photochemistry and Technology GHY2023KF013European Union's Horizon 2020 research and innovation programGeneralitat de CatalunyaInnovation Team in Key Areas of the Innovation Talent Promotion Plan (2021) of MOST, ChinaNational Key R&D Program of China 2021YFA1200083National Natural Science Foundation of China 21975195Secretaria d'Universitats i Recerca del Departament d'Empresa i Coneixement de la Generalitat de Catalunya 2021 SGR 01606

6 · The paper itself

Abstract

Active matter, encompassing both natural and artificial systems, utilizes environmental energy to sustain autonomous motion, exhibiting unique non-equilibrium behaviors. Artificial active matter (AAM), such as nano/micromotors, holds transformative potential in precision medicine by enhancing drug delivery and enabling targeted therapeutic interventions. Under the demand for increasing intelligence in AAM, controlling their non-equilibrium processes within complex in vivo environments presents significant challenges. Endogenous fields-biological fields generated within living systems-play a pivotal role in guiding natural active matter's (NAM) directional migration and collective transformations, offering a strategy for in vivo control of non-equilibrium systems. Research in NAMs-inspired AAMs spans biology, chemistry, materials science, engineering, and physics, yet communication barriers among disciplines often impede progress. This review seeks to bridge these gaps by summarizing the key characteristics of chemical and physical endogenous fields in biological contexts such as tumors, wounds, and inflammation. It explores how natural and artificial active matter sense, transmit, and execute responses to these fields, and discusses how insights from natural systems can inform the design of synthetic counterparts. Potential issues and prospects of this research direction are also discussed. It is hoped that this review fosters interdisciplinary collaborations and propels the development of intelligent active matter for biomedical applications.

Indexed as

NanotechnologyAnimalsHumansPrecision Medicineactive mattercollective behaviorendogenous fieldsnanomotors

Identifiers

PMID40916206

DOI10.1002/adma.202503091

PMCPMC12617066

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.