ArticleInfluenza and other respiratory viruses2025
Cost-Effectiveness Analysis of a Maternal Vaccination Program Against Respiratory Syncytial Virus in Norway.
Article in Influenza and other respiratory viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Review
- Cost-Effectiveness Analysis of a Maternal Vaccination Program Against Respiratory Syncytial Virus in Norway.Influenza and other respiratory viruses · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundRespiratory syncytial virus (RSV) is recognized as the primary cause of hospitalizations among children with lower respiratory tract infections in developed countries, placing a significant burden on both patients and healthcare systems. The efficacy, safety, and immunogenicity of maternal vaccination with the novel RSVpreF vaccine have been evaluated in a Phase III clinical trial, showing a decreased risk of severe infection in infants. Our study assesses the cost-effectiveness of the RSVpreF vaccine and seasonal variation of costs in a Norwegian setting.
methodsA Markov model was used to estimate the clinical outcomes, costs, and quality-adjusted life years of a hypothetical cohort of Norwegian infants born during a single RSV season. A seasonal vaccination program with RSVpreF vaccine was compared to no intervention by means of an incremental cost-effectiveness ratio (ICER) from extended healthcare and societal perspectives.
resultsA seasonal maternal vaccination program with RSVpreF in Norway is cost-effective from both a healthcare and societal perspective, given the Norwegian willingness-to-pay threshold range. The program could prevent 27% of the yearly RSV-associated hospital admissions, as well as 14% and 24% of the yearly RSV-associated primary care and outpatient visits. A 10% increase/decrease in hospitalization costs during the winter/summer months leads to a 26% reduction in the ICER from a healthcare perspective and turns the intervention into a dominant strategy from a societal one.
conclusionsBased on the RSVpreF vaccine's list price in Norway, the seasonal vaccination program is cost-effective from both the healthcare and societal perspectives, considering a willingness-to-pay threshold of 500,000 NOK.
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