Evidence map›Paper›PMID 40915974›Full record

ArticleJournal of clinical periodontology2026

The Interplay Between Lifestyle and Oral/Faecal Microbial Profiles Among Periodontal Disease Patients: A Cross-Sectional Study.

Marcella Costa Ribeiro, Ana Paula Vieira Colombo, Adriana Miranda de Oliveira, Talita Gomes Baêta Lourenço, Heitor Marques Honório, Ellen Cristini de Freitas, Michel Reis Messora, Flávia Aparecida Chaves Furlaneto

Abstract read
In one paragraph

Article in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marcella Costa RibeiroDepartment of Oral and Maxillofacial Surgery and Periodontology, Ribeirao Preto School of Dentistry, University of Sao Paulo (USP), Ribeirao Preto, Brazil.
Ana Paula Vieira ColomboSchool of Dentistry, Postgraduate Program in Periodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0002-2061-1840
Adriana Miranda de OliveiraSchool of Dentistry, Postgraduate Program in Periodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-9096-9576
Talita Gomes Baêta LourençoSchool of Dentistry, Postgraduate Program in Periodontics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Heitor Marques HonórioDepartment of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.ORCID 0000-0003-0231-3409
Ellen Cristini de FreitasSchool of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, Brazil.ORCID 0000-0002-7343-2002
Michel Reis MessoraDepartment of Oral and Maxillofacial Surgery and Periodontology, Ribeirao Preto School of Dentistry, University of Sao Paulo (USP), Ribeirao Preto, Brazil.ORCID 0000-0001-8485-9645
Flávia Aparecida Chaves FurlanetoDepartment of Oral and Maxillofacial Surgery and Periodontology, Ribeirao Preto School of Dentistry, University of Sao Paulo (USP), Ribeirao Preto, Brazil.ORCID 0000-0002-8072-3983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo characterise periodontal and faecal microbiomes of individuals with periodontal health (PH) and diseases, and evaluate associations with periodontal, sociodemographic, anthropometric, nutritional and lifestyle factors. MATERIALS AND

methodsDental biofilm and faecal samples from individuals (n = 24/group) with PH, gingivitis (GG) and periodontitis (PE) were sequenced (16S rRNA). Anthropometric data and questionnaires on demographics, lifestyle, diet and intestinal habits were collected. Data were statistically analysed (p < 0.05).

resultsGG and PE groups showed higher age, BMI, waist/abdominal circumferences and trans-fat intake and lower selenium and vitamin E intake compared to PH. Individuals with PE had higher hip circumference and lower income, education and intake of iron as well as vitamins A and B9. PE microbiomes (oral and faecal) showed distinct compositions, with the highest number of unique oral species. Faecal richness was lower in PE and GG compared to PH. Specific microbial taxa correlated with periodontal status and host factors.

conclusionPeriodontal and faecal microbiomes vary across periodontal conditions. Discriminant analysis classified 77% of individuals by periodontal status, with key markers for PE including older age, poor dietary quality and distinct microbial oral and faecal signatures. These findings highlight the role of clinical, dietary and microbial factors in periodontal disease profiling.

Indexed as

FecesGastrointestinal MicrobiomeLife StyleMouthPeriodontitisAdultAnthropometryBiofilmsBrazilCross-Sectional StudiesDietDiscriminant AnalysisEatingFemaleHumansMaleRNA, Ribosomal, 16Sintestinal microbiomemetagenomemicrobiotaperiodontal diseases

Identifiers

PMID40915974
PMCPMC12695455

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.