Evidence map›Paper›PMID 40915655›Full record

ArticleJournal of microbiology and biotechnology2025

Shiga Toxin Type 2 Aggravates G1/S Phase Cell Cycle Arrest, Mediating Caspase-Independent Cell Death under Hyperosmotic Conditions in the Kidney.

So-Hyeon Park, Kyung-Soo Lee, Jun Young Park, Dae-Soo Kim, Hyun-Soo Cho, Ji Heon Noh, Chang-Ung Kim, Moo-Seung Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

So-Hyeon ParkEnvironmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Kyung-Soo LeeEnvironmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Jun Young ParkEnvironmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Dae-Soo KimDigital Biotech Innovation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Hyun-Soo ChoDepartment of Biomolecular Science, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34113, Republic of Korea.
Ji Heon NohDepartment of Biochemistry, Chungnam National University, Daejeon 34134, Republic of Korea.
Chang-Ung KimEnvironmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Moo-Seung LeeEnvironmental Diseases Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shiga toxin (Stx) is a virulence factor produced by

Indexed as

Cell Cycle CheckpointsG1 Phase Cell Cycle CheckpointsKidneyShiga Toxin 2AnimalsApoptosisCaspasesCell DeathEndoplasmic Reticulum StressEpithelial CellsHSP70 Heat-Shock ProteinsHumansOsmotic PressureReactive Oxygen SpeciesShiga-Toxigenic Escherichia coliShigella dysenteriaeCaspasesHSP70 Heat-Shock ProteinsReactive Oxygen SpeciesShiga Toxin 2Sodium Chloridecaspase-independent cell deathG1/S phase cell cycle arresthemolytic uremic syndromehyperosmotic conditionShiga toxin

Identifiers

PMID40915655
PMCPMC12420956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.