Trial reportArchives of physical medicine and rehabilitation2026
Quantifying Exercise Intensity to Predict Changes in Walking Capacity in Individuals with Chronic Stroke.
Trial report in Archives of physical medicine and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Is training speed an accurate predictor of who attains a minimal clinically important difference in the six-minute walk test in people with chronic stroke?Topics in stroke rehabilitation · 2025Trial
- Using Exercise Intensity to Predict a Minimal Clinically Important Difference in the Six-Minute Walk Test in People with Chronic Stroke.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo examine whether exercise intensity, quantified as heart rate or training speed, predicts walking outcomes in people with chronic stroke.
designThis is a secondary analysis from a larger randomized controlled trial ("Promoting Recovery Optimization of Walking Activity in Stroke"; NIH1R01HD086362).
settingFour outpatient rehabilitation clinics.
participantsParticipants with chronic stroke with a walking speed of 0.3-1.0 m/s and step activity of <8000 steps per day. This analysis included participants (N=169; age, 63.1±12.5, 46% women) with complete baseline and postintervention data.
interventionsParticipants were randomized into (1) fast-walking training or (2) fast-walking training and step-activity monitoring behavioral group. Of importance, participants received up to 36 sessions of 30-minute high-intensity treadmill walking training across 12 weeks.
main outcome measuresThe primary outcomes were a baseline-to-postintervention change in 6-minute walk test distance and fastest walking speed. Exercise intensity was quantified as either a percentage of heart rate reserve or self-selected walking speed.
resultsTwo separate multiple linear regressions with robust errors analyzed the relationship of exercise intensity metrics (% heart rate, training speed) on baseline-to-postintervention changes in 2 walking capacity outcomes (6-minute walk test, fastest walking speed) after accounting for covariates. Training speed was a significant predictor of both a change in 6-minute walk test distance (b=0.359; 95% CI, 0.108-0.610; P=.005) and fastest walking speed (b=0.001; 95% CI, 0.001-0.002; P=.003). Heart rate was not a significant predictor of either outcome (both P>.373).
conclusionsTraining speed significantly predicts changes in walking capacity outcomes in people with chronic stroke following a fast-walking treadmill intervention. This suggests rehabilitation clinicians may use training speed as the metric of exercise intensity when prescribing walking interventions to people with chronic stroke.
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