Evidence map›Paper›PMID 40915309›Full record

ReviewLancet (London, England)2025

Shigellosis.

Jennifer Hendrick, Rubhana Raqib, Zannatun Noor, A S G Faruque, Rashidul Haque, William A Petri

Abstract readReview
In one paragraph

Review in Lancet (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Isolation and characterization of lyticFrontiers in cellular and infection microbiology · 2026
    Article
  9. Clinical outcomes of carbapenem vs. non-carbapenem therapy in hospitalized adults with shigellosis.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer HendrickDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA. Electronic address: jms7uq@uvahealth.org.
Rubhana RaqibNutrition Research Division, icddr,b, Dhaka, Bangladesh.
Zannatun NoorInfectious Disease Division, icddr,b, Dhaka, Bangladesh.
A S G FaruqueNutrition Research Division, icddr,b, Dhaka, Bangladesh.
Rashidul HaqueInfectious Disease Division, icddr,b, Dhaka, Bangladesh.
William A PetriDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA.

Funding

The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
Active and passive humoral immunity to enteric adenovirus infection in Bangladeshi childrenK23AI187708 · NIAID · UNIVERSITY OF VIRGINIA · PI Jennifer Marie Hendrick · 2025 to 2026
$384k
NCATS NIH HHS KL2 TR003016NCATS NIH HHS UL1 TR003015NIAID NIH HHS K23 AI187708
6 · The paper itself

Abstract

Shigella is a Gram-negative, facultative intracellular, gastric acid-resistant bacterium of the Enterobacteriaceae family, which includes four serogroups: Shigella dysenteriae, Shigella sonnei, Shigella flexneri, and Shigella boydii. Globally, shigellosis is the most common cause of invasive bloody diarrhoea in children younger than 5 years. Humans are the only natural reservoir and an inoculum of only 10-100 organisms is required for infection. Rising antibiotic resistance rates increasingly reduce the ability to adequately treat severe disease. The prevention of infection with vaccination and sanitation strategies remains a crucial step in reducing worldwide morbidity and mortality.

Indexed as

Dysentery, BacillaryShigellaAnti-Bacterial AgentsChildChild, PreschoolGlobal HealthHumansShigella VaccinesAnti-Bacterial AgentsShigella Vaccines

Identifiers

PMID40915309
PMCPMC12704457

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.