Evidence map›Paper›PMID 40914750›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2025

Disentangling the effects of corticotrophin releasing factor and GABA release from the bed nucleus of the stria terminalis on ethanol self-administration in mice.

Carol A Gianessi, Harold L Haun, Dipa Pati, Tori Sides, Shannon L D'Ambrosio, Willem P Kelson, Raul Hernandez, Graydon B Gereau, Kristen Boyt, Clyde W Hodge and 1 more

Abstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Bed Nucleus of the Stria Terminalis (BNST) neurons containing the serotonin 5HTNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Carol A GianessiBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-7662-8636
Harold L HaunBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Dipa PatiBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0001-6303-4871
Tori SidesBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Shannon L D'AmbrosioBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Willem P KelsonBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Raul HernandezBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Graydon B GereauBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kristen BoytBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Clyde W HodgeBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Thomas L KashBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. tkash@email.unc.edu.ORCID http://orcid.org/0000-0002-4747-4495

Funding

UNC ARC Information/Dissemination CoreP60AA011605 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A Herman · 2003 to 2026
$46.3M
Supplement to Molecular and Cellular Studies on Alcohol's ActionsT32AA007573 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FULTON T CREWS, Thomas L. Kash · 1997 to 2026
$9.3M
Probing Ethanol Induced Acceleration of Hindbrain and Amygdalar Pathology in an Alzheimer’s Disease ModelU01AA020911 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas L. Kash, Zoe Anastasia McElligott · 2012 to 2026
$5.8M
The Role of Serotonin in Alcohol-Withdrawal Induced AnxietyR01AA019454 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas L. Kash · 2010 to 2026
$5.6M
Core 1: Brain Circuit Validation CoreU24AA025475 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KASH, THOMAS L. · 2017 to 2021
$1.1M
Role of nociceptin-containing neurons of the lateral septum in binge-like alcohol consumptionF32AA030494 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAUN, HAROLD L · 2022 to 2023
$139k
NIAAA NIH HHS F32 AA030494NIAAA NIH HHS P60 AA011605NIAAA NIH HHS R01 AA019454NIAAA NIH HHS T32 AA007573NIAAA NIH HHS U01 AA020911NIAAA NIH HHS U24 AA025475U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) F32AA030494U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) P60AA011605U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) R01AA019454U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) T32AA007573U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) U01AA020911U.S. Department of Health & Human Services | NIH | National Institute on Alcohol Abuse and Alcoholism (NIAAA) U24AA025475
6 · The paper itself

Abstract

Excessive alcohol use causes a great deal of harm and negative health outcomes. Corticotrophin releasing factor (CRF), a stress-related neuropeptide, has been implicated in binge ethanol intake and ethanol dependence in rodents. CRF containing neurons in the bed nucleus of the stria terminalis (BNST

Indexed as

Alcohol DrinkingCorticotropin-Releasing HormoneEthanolgamma-Aminobutyric AcidSeptal NucleiAnimalsCentral Nervous System DepressantsConditioning, OperantFemaleMaleMiceMice, Inbred C57BLNeuronsSelf AdministrationCentral Nervous System DepressantsCorticotropin-Releasing HormoneEthanolgamma-Aminobutyric Acid

Identifiers

PMID40914750
PMCPMC12603268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.