Evidence map›Paper›PMID 40913645›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Assessing the need for multimodal care in anorexia and cachexia patients with advanced cancer referred to palliative care: a secondary analysis of a multicenter survey in Japan.

Sayaka Arakawa, Koji Amano, Saori Koshimoto, Satomi Okamura, Tatsuma Sakaguchi, Yoshinobu Matsuda, Akihiro Tokoro, Takashi Takeuchi, Naoharu Mori, Eriko Satomi

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The multidimensional impact of malnutrition in incurable cancer.Current opinion in supportive and palliative care · 2026
    Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sayaka Arakawa *Department of Palliative Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Koji Amano *Department of Supportive and Palliative Care, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan. kojiamano4813@gmail.com.
Saori KoshimotoLiaison Psychiatry and Psycho-oncology Unit, Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Satomi OkamuraDepartment of Medical Innovation, Osaka University Hospital, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tatsuma SakaguchiDepartment of Surgery, Kansai Medical University Kori Hospital, 8-45 Korihondori-cho, Neyagawa, Osaka, 572-8551, Japan.
Yoshinobu MatsudaDepartment of Psychosomatic Internal Medicine and Supportive and Palliative Care Team, NHO Kinki Chuo Chest Medical Center, 1180 Nagasone-cho, Kita-ku, Sakai city, Osaka, 591-8555, Japan.
Akihiro TokoroDepartment of Psychosomatic Internal Medicine and Supportive and Palliative Care Team, NHO Kinki Chuo Chest Medical Center, 1180 Nagasone-cho, Kita-ku, Sakai city, Osaka, 591-8555, Japan.
Takashi TakeuchiLiaison Psychiatry and Psycho-oncology Unit, Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Naoharu MoriDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
Eriko SatomiDepartment of Palliative Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

Funding

JSPS KAKENHI 23K10970
6 · The paper itself

Abstract

purposeThere are no methods for assessing the need for multimodal care in cancer cachexia. We examined nine components in evaluating needs among advanced cancer patients.

methodsThis was a self-administered survey. Participants rated their nutrition impact symptoms (NISs) using a numerical rating scale, dietary intake using the Ingesta-Verbal/Visual Analogue Scale, and needs for nine components of multimodal care using a 7-point Likert scale. They completed the Hospital Anxiety and Depression Scale (HADS), Distress Thermometer, and Impact Thermometer questionnaires. They were divided into high- and low-need groups based on the median of the total scores for the nine components. We compared the groups and performed a multivariate logistic regression analysis to determine the association between need, NISs, dietary intake, and each scale.

resultsUltimately, 170 respondents were grouped into the high-need (n = 88) and low-need (n = 82) groups. There were no significant differences in their characteristics. The high-need group had significantly higher scores for NISs as well as higher HADS-Anxiety, Distress Thermometer, and Impact Thermometer scores. Four or more NISs with a score ≥ 4 (odds ratio (OR) 2.24, 95% confidence interval (CI) 1.09-4.60), a HADS-Anxiety score ≥ 8 (OR 2.42, 95% CI 1.22-4.79), a Distress Thermometer score ≥ 4 (OR 6.10, 95% CI 2.36-15.76), and an Impact Thermometer score ≥ 3 (OR 3.87, 95% CI 1.57-9.50) were associated with a high need.

conclusionsThe nine components were associated with NISs, anxiety, and distress. They were useful in evaluating needs for multimodal care.

Indexed as

AnorexiaCachexiaNeeds AssessmentNeoplasmsPalliative CareAdultAgedAged, 80 and overAnxietyCombined Modality TherapyDepressionFemaleHumansJapanLogistic ModelsMaleCachexiaCancerDistressPalliative careSymptoms

Identifiers

PMID40913645

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.