ArticleJACC. Case reports2025
First Reported Case of Intracardiac Kimura Disease.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundKimura disease is a rare inflammatory condition that typically manifests with subcutaneous nodules of the head and neck. This is the first documented case of intracardiac Kimura disease. CASE SUMMARY: A 57-year-old woman presented with a heart murmur and dyspnea. Echocardiography uncovered a 3-cm mass obstructing the right ventricular outflow tract. The mass was resected, and the pulmonary valve was replaced. Pathology yielded the diagnosis of Kimura disease. DISCUSSION: Treatment of Kimura disease may include surgery, steroids, and radiation therapy. There is potential for disease recurrence. TAKE-HOME MESSAGES: This is the first reported case of intracardiac Kimura disease, an inflammatory condition usually involving the head and neck. The working diagnosis for the right ventricular outflow tract mass was myxoma until final pathologic analysis was obtained. Our patient underwent surgical resection without steroids or radiation. Active surveillance with patient follow-up and surveillance echocardiography over 1 year demonstrated no recurrence.
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