Evidence map›Paper›PMID 40913535›Full record

ReviewThe European journal of neuroscience2025

Looking at Both Sides: Integrating Data From Both Hemispheres Is Crucial in Rodent Neuroscience.

Annakarina Mundorf, Sebastian Ocklenburg

Abstract readReview
In one paragraph

Review in The European journal of neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Annakarina MundorfMedical School Hamburg, Institute for Systems Medicine and Department of Human Medicine, Hamburg, Germany.ORCID 0000-0002-3667-5339
Sebastian OcklenburgMedical School Hamburg, ICAN Institute for Cognitive and Affective Neuroscience, Hamburg, Germany.ORCID 0000-0001-5882-3200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the overwhelming prevalence of rodent-based research in neuroscience, with over 8700 studies published until March 2025 in the European Journal of Neuroscience alone (based on a targeted PubMed search using rodent-related keywords), one striking reality stands out: only a handful-24 studies-have explicitly addressed hemispheric asymmetries (using the same search with asymmetry-related terms). While this number is not exhaustive, it serves to exemplify the relatively limited focus on hemispheric lateralization in rodent studies. This notable gap in the literature highlights a pervasive underappreciation for the role of brain lateralization in rodents, a critical area of investigation that has been widely studied in human neuroscience but remains largely unexplored in animal models. In light of this, it becomes clear that a fundamental shift in research priorities is needed to unlock the full potential of rodent models in understanding brain organization and its implications for neurological and psychiatric disorders.

Indexed as

BrainFunctional LateralityNeurosciencesAnimalsHumansRodentiahemispheric asymmetryhistologylateralizationneuroimaging techniquesstandardized protocols

Identifiers

PMID40913535
PMCPMC12413770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.