ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
The effect of preoperative oral carbohydrate on the perioperative period of fibula free flap surgery in patients with oral cancer: a retrospective study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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6 authors.
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Abstract
objectiveThis study examines the effects of preoperative oral carbohydrates on the perioperative period of Fibula Free Flap surgery in oral cancer patients, aiming to enhance postoperative recovery.
methodsThe study involved 89 patients who underwent fibula flap reconstruction surgery from January to December 2023. Patients were divided into control and experimental groups based on admission time. The control group followed standard fasting guidelines, while the experimental group received 800 mL and 200 mL of carbohydrates solution orally at 10 and 2 h pre-surgery, respectively. Data collected for both groups included comfort levels, blood glucose, surgical duration, intraoperative blood loss, fluid replacement, albumin, prealbumin, hemoglobin, PCT, IL-6, flap crisis, wound infection, bleeding, thrombosis, gastrointestinal reactions, extubation time, hospital stay, and total cost. All data were statistically analyzed.
resultsThe experimental group reported significantly lower thirst and hunger one hour pre-surgery (p < 0.0001) and had lower blood glucose levels one day post-surgery (p = 0.0003) compared to the control group. No significant differences were observed in other preoperative or postoperative measures.
conclusionsPreoperative oral carbohydrates improve comfort and stabilize blood glucose levels in patients undergoing oral cancer fibula flap surgery, positively influencing perioperative management. This approach is beneficial for patients receiving this type of surgery.
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