ReviewNature reviews. Neuroscience2025
The emerging roles of long non-coding RNAs in the nervous system.
Review in Nature reviews. Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Discovery of a mutation-containing circRNA in polyglutamine disease through systematic analysis of RNAs with CAG repeats.RNA biology · 2026Article
- Spatial Total RNA Sequencing of Formalin-Fixed Paraffin-Embedded Tissue by spRandom-seq.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- ThebioRxiv : the preprint server for biology · 2026Article
- Pnky lncRNA secondary structure maps identify functional regions that control neurogenesis in neural stem cells.Cell reports · 2026Article
- Review
- Role of non-coding RNAs in OOncology letters · 2026Review
- Uncovering Spatiotemporal and Functional Dynamics of Long Non-coding RNAs During Alzheimer's Progression in the Human Brain at Single-Cell Resolution.Molecular neurobiology · 2026Article
- Retinoic Acid and Long Noncoding RNAs Crosstalk: Implications for Neuronal Differentiation and Diseases.Molecular neurobiology · 2026Review
- The emerging role of epigenetic regulation in pain sensitization associated with headache disorders.The journal of headache and pain · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tens, if not hundreds, of thousands of long non-coding RNAs (lncRNAs) are transcribed from mammalian genomes, especially in the brain, wherein most exhibit region-specific and/or cell-specific expression patterns. Many lncRNAs are nuclear-localized and appear to be the products of developmental enhancers, whereas others are found in the cytoplasm, including at the synapse. Here, we describe the lncRNAs that have been shown to have roles in various aspects of brain development, synaptic function, learning, behaviour and brain disorders. Our emerging understanding indicates that lncRNAs direct many, if not most, of the regulatory transactions that give rise to the structure of the brain and modulate its functions, probably through their guidance of relatively generic effector proteins. Although they hold promise as targets for therapeutic interventions, a concerted effort will be required to characterize the structures, functions, spatial distribution and interacting partners of the lncRNAs expressed in the brain, most of which have not been studied. We suggest that the lncRNAs transcribed from genomic regions associated with human neurological traits and disorders be prioritized for analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.