Evidence map›Paper›PMID 40912911›Full record

Trial reportJournal of neurology, neurosurgery, and psychiatry2025

Clinical outcomes and economic impact of a digital telemedicine intervention in patients with functional motor disorders: a single-blind, randomised controlled trial.

Marialuisa Gandolfi, Stefano Landi, Angela Sandri, Ilaria Antonella Di Vico, Christian Geroin, Zoe Menaspà, Gianluca Maistri, Melania Fasoli, Federico Schena, Michele Tinazzi and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neurology, neurosurgery, and psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05345340 (Effectiveness of Telemedicine on Health Outcomes), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05345340 naunknown statusnot on this map

Effectiveness of Telemedicine on Health Outcomes (Clinical, Humanistic, Economic) in the Management of Patients With Functional Motor Disorder: Randomised Controlled Clinical Trial

TypeinterventionalSponsorUniversita di VeronaRan2022 to 2024Enrolled62ConditionsFunctional Movement DisorderArmsTelemedicine, Usual care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marialuisa Gandolfi *Department of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy marialuisa.gandolfi@univr.it.ORCID http://orcid.org/0000-0002-0877-4807
Stefano Landi *Department of Management, University of Verona, Verona, Italy.
Angela SandriDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0003-0462-3945
Ilaria Antonella Di VicoDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.
Christian GeroinDepartment of Surgery, Dentistry, Paediatrics and Gynaecology, Universita degli Studi di Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-2370-7063
Zoe MenaspàDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0001-9754-2815
Gianluca MaistriDepartment of Management, University of Verona, Verona, Italy.
Melania FasoliDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.ORCID http://orcid.org/0009-0002-5664-393X
Federico SchenaDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.
Michele TinazziDepartment of Neuroscience, Biomedicine and and Movement Sciences, University of Verona, Verona, Italy.
Chiara LeardiniDepartment of Management, University of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional motor disorders (FMD) cause long-term disability and economic burden. There is a need for multidisciplinary interventions to manage both motor and non-motor symptoms. We aim to evaluate the clinical and economic effects of integrating digital telemedicine into multidisciplinary FMD management.

methodsThis single-blind, randomised controlled trial involved patients with FMD. They were randomly assigned to receive 5-day multidisciplinary rehabilitation with either a digital telemedicine or a standard care programme. The digital telemedicine group received remote management and wearable sensors. A blinded evaluator assessed primary and secondary outcomes at baseline, post-treatment, 12-week and 24-week follow-ups. The primary outcomes were changes in motor symptoms. The secondary outcomes were changes in non-motor symptoms, quality of life (QoL) and mobility in unsupervised settings. The incremental cost-effectiveness ratio (ICER) and quality-adjusted life years (QALYs) were calculated at 24 weeks.

resultsOf the total of 62 patients, half made up the digital telemedicine group (n=31, 40.82% female, mean age 42.55±12.65 years) and half the standard care group (n=31, 59.18% female, mean age 43.77±14.44 years). The mental QoL score for the standard care group was lower (p=0.045) and declined compared with the digital telemedicine group (p=0.034), with lower scores at follow-up (p=0.03). At 24 weeks, the ICER (€5503/QALY) showed that digital telemedicine, despite higher initial costs, yielded 0.037 additional QALYs and reduced healthcare use during follow-up.

conclusionsDespite similar improvements in motor symptoms in both groups, digital telemedicine offers an effective adjunct to maintain mental health QoL and reduces healthcare costs in the long-term management of FMD. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov ID: NCT05345340.

Indexed as

Conversion DisorderTelemedicineAdultCost-Benefit AnalysisFemaleHumansMaleMiddle AgedQuality-Adjusted Life YearsQuality of LifeSingle-Blind MethodTreatment OutcomeFUNCTIONAL NEUROLOGICAL DISORDERHEALTH ECONOMICSQUALITY OF LIFEREHABILITATION

Identifiers

PMID40912911
PMCPMC12703269

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.