Evidence map›Paper›PMID 40912380›Full record

ArticleAnnals of epidemiology2025

Validation of data in the Veteran health administration electronic medical record for identification of tobacco use.

Brian J Douthit, Julie Kim, Amber J Hackstadt, Daniel Park, Robert Winter, Jessica Deere, Lucy B Spalluto, Sally J York, Fred Hendler, Robert S Dittus and 5 more

Abstract readValidation Study
In one paragraph

Article in Annals of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Brian J DouthitVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Julie KimVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Amber J HackstadtVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States.
Daniel ParkVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Robert WinterVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Jessica DeereVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
Lucy B SpallutoVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Center for Clinical Quality and Implementation Research, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, United States; Veterans Health Administration-Tennessee Valley Healthcare System, Medicine Service, Nashville, TN, United States.
Sally J YorkVanderbilt-Ingram Cancer Center, Nashville, TN, United States; Veterans Health Administration-Tennessee Valley Healthcare System, Medicine Service, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Fred HendlerRex Robley VA Medical Center, Medicine Service, Louisville, KY, United States.
Robert S DittusVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Center for Clinical Quality and Implementation Research, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Dana E ChristoffersonVeterans Health Administration, Office of Mental Health, Washington, DC, United States.
Michael E MathenyVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Hilary A TindleVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Vanderbilt-Ingram Cancer Center, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Christianne L RoumieVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Center for Clinical Quality and Implementation Research, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Health Policy, Vanderbilt University, Nashville, TN, United States.
Jennifer A LewisVeterans Health Administration, VA Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC), and VETWISE-LHS Center of Innovation, Nashville, TN, United States; Vanderbilt-Ingram Cancer Center, Nashville, TN, United States; Center for Clinical Quality and Implementation Research, Vanderbilt University Medical Center, Nashville, TN, United States; Veterans Health Administration-Tennessee Valley Healthcare System, Medicine Service, Nashville, TN, United States; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address: jennifer.a.lewis@vumc.org.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Vanderbilt Scholars in T4 Translational Research (V-STTaR) ProgramK12HL137943 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KRIPALANI, SUNIL, ROUMIE, CHRISTIANNE L. · 2017 to 2021
$2.9M
AHRQ HHS K12 HS026395AHRQ HHS P30 HS029767CSRD VA I01 CX002686Intramural VA VA999999NCI NIH HHS P30 CA068485NHLBI NIH HHS K12 HL137943
6 · The paper itself

Abstract

purposeTobacco use is not commonly represented as computable information in the electronic health record (EHR). We developed an algorithm in the Veterans Health Administration (VHA) to identify tobacco ever-use among Veterans.

methodsWe used the VHA corporate data warehouse to develop an algorithm comprised of multiple data types (health factors [semi-structured template data entry and decision support tools], billing, orders, medication, and encounter codes) to identify tobacco ever-use (current or former) versus never use. Algorithm accuracy was compared to two reference standards: (1) EHR abstraction cohort and (2) Veteran self-reported survey cohort. We calculated the sensitivity and positive predictive values (PPV) for the algorithm and stratified by its data types for the EHR abstraction cohort. We calculated the sensitivity, specificity, PPV, and negative predictive value (NPV) for the algorithm and stratified by its data types for the survey cohort.

resultsThe algorithm correctly identified 424 of 426 individuals with tobacco ever-use when compared to data abstracted from the EHR: sensitivity 1.00 (95 % CI 0.98-1.00); PPV 1.00 (95 % CI 0.98-1.00). Compared to survey data, the algorithm correctly identified 514 of 547 participants with tobacco ever-use: sensitivity 0.94 (95 % CI 0.92-0.96); PPV 0.88 (95 % CI 0.85-0.91). The specificity was 0.53 (95 % CI 0.45-0.62), and NPV of 0.70 (95 % CI 0.61-0.79). Of all data types, health factors had the highest sensitivity in both cohorts.

conclusionsThis novel tool had excellent sensitivity and PPV for tobacco ever-use in two cohorts. Future research should study this tool to support preventive healthcare services.

Indexed as

AlgorithmsElectronic Health RecordsTobacco UseVeteransAdultAgedFemaleHumansMaleMiddle AgedSelf ReportSensitivity and SpecificityUnited StatesUnited States Department of Veterans AffairsAlgorithmsElectronic health recordHealth information systemsPreventive health servicesTobacco useValidation studyVeterans

Identifiers

PMID40912380
PMCPMC12530477

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.