Evidence map›Paper›PMID 40911930›Full record

ArticleThe Journal of international medical research2025

A prospective case-control study: Analysis of the analgesic effect of acetaminophen-mannitol injection after endoscopic lumbar discectomy.

Jie-Bin Huang, Yin-Feng Guo, Cheng-Zhao Li, Wei-Xiong Chen, Bai-Yong Zhu, Yu Lei, Wei-Dong Jiao, Li-Bin Zheng, Hou-Jun Xue

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Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jie-Bin HuangDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.ORCID 0009-0003-6869-2218
Yin-Feng GuoDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Cheng-Zhao LiDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Wei-Xiong ChenDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Bai-Yong ZhuDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Yu LeiDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Wei-Dong JiaoDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Li-Bin ZhengDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.
Hou-Jun XueDepartment of Orthopedics, Sanshui Hospital, Zhujiang Hospital, Southern Medical University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo investigate the analgesic effects of acetaminophen-mannitol injections after endoscopic lumbar discectomy.MethodsThis is a prospective case-control study involving 60 patients who were randomly selected from those who underwent endoscopic lumbar discectomy for lumbar disc herniation or lumbar spinal stenosis at Sanshui District People's Hospital of Foshan between April and September 2024. Two groups were formed by randomly assigning patients, with each group containing 30 individuals. The observation group underwent treatment with acetaminophen-mannitol for pain relief, whereas the control group was administered oral etoricoxib and intravenous mannitol. A comparison was made between the analgesic effects of the two groups.ResultsCompared with the control group, the observation group showed significantly lower visual analog scale scores on the first, third, and seventh days after operation (

Indexed as

AcetaminophenDiskectomyEndoscopyIntervertebral Disc DisplacementLumbar VertebraeMannitolPostoperative PainAdultAnalgesicsCase-Control StudiesFemaleHumansMaleMiddle AgedPain MeasurementProspective StudiesAcetaminophenAnalgesicsMannitolAcetaminophen–mannitol injectionanalgesiaendoscopic lumbar discectomyenhanced recovery after surgeryprospective case–control study

Identifiers

PMID40911930
PMCPMC12413524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.