ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Practice effects on digital cognitive assessment tools: insights from the defense automated neurobehavioral assessment battery.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Practice effects on digital cognitive assessment tools: insights from the defense automated neurobehavioral assessment battery.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introductionDigital cognitive assessments offer a promising approach to monitoring cognitive impairments, but repeated use can introduce practice effects, potentially masking changes in cognitive status. We evaluated practice effects using the Defense Automated Neurobehavioral Assessment (DANA), a digital battery designed for cognitive monitoring.
methodsWe analyzed data from 116 participants from the Boston University Alzheimer's Disease Research Center, comparing response times across two DANA sessions, around 90 days apart, while controlling for cognitive status, sex, age, and education.
resultsModest practice effects were found, and cognitive impairment was associated with slower response times in several tasks. Classification models, including logistic regression and random forest classification, achieved accuracies of up to 71% in assessing cognitive status. DISCUSSION: Our study establishes a framework for evaluating practice effects in digital cognitive assessment tools. Future work should expand the sample size and diversity to enhance the generalizability of findings in broader clinical contexts. HIGHLIGHTS: We systematically evaluated practice effects using the DANA battery as a case study. Modest practice effects were observed across two testing sessions, with a median inter-session interval of 93 days. Cognitive impairment was significantly associated with slower response times in key tasks (p < 0.001). Our framework offers a systematic approach for evaluating practice effects in digital cognitive tools.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.