SynthesisJournal of veterinary internal medicine
Iron-Limited Erythropoiesis in Dogs and Cats: A Systematic Review and Meta-Analysis of Current Evidence Examining Mean Corpuscular Volume, Mean Reticulocyte Volume, and Reticulocyte Hemoglobin Content.
Synthesis in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Iron-Limited Erythropoiesis in Dogs and Cats: A Systematic Review and Meta-Analysis of Current Evidence Examining Mean Corpuscular Volume, Mean Reticulocyte Volume, and Reticulocyte Hemoglobin Content.Journal of veterinary internal medicinePooled it
- Immature platelet and reticulocyte fractions as dynamic biomarkers of bone marrow activation in dogs and humans: a comprehensive review.Veterinary and animal science · 2026Review
- Antiepileptic drug therapy in companion animals: New perspectives on clinical pathology monitoring.Veterinary and animal science · 2026Review
- Differential diagnosis of microcytic hypochromic anemia in dogs: the role of hepcidin and reticulocyte hemoglobin indices.Veterinary research communications · 2026Review
- Hypoxia-inducible factor prolyl hydroxylase inhibitor as a new therapeutic option for treating anemia in feline chronic kidney disease.Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundIron-limited erythropoiesis (ILE) is a common condition in dogs and cats, which can lead to anemia; therefore, monitoring with erythrocyte and reticulocyte indices is recommended.
objectivesTo compare the values of mean corpuscular volume (MCV), mean reticulocyte volume (MCVr), and reticulocyte hemoglobin content (CHr) in dogs and cats with ILE.
methodsSystemative review and meta-analysis. We conducted a systematic search using PRISMA criteria in PubMed, ScienceDirect, and Google Scholar up to 2024. It focused on erythrocyte and reticulocyte indices, such as MCV, MCVr, and CHr, in dogs and cats with ILE.
resultsThis meta-analysis included eight articles. For dogs, the random effect sizes were 2.86 (0.55-5.18) for MCV, 2.18 (0.87-3.58) for MCVr, and 4.73 (1.37-8.08) for CHr. For cats, the effect sizes were 0.85 (0.19-1.5) for MCV, 3.45 (0.49-6.41) for MCVr, and 2.51 (0.29-4.74) for CHr. The analysis revealed I CONCLUSION AND CLINICAL IMPORTANCE: The findings revealed significant differences in reticulocyte indices, MCVr in cats, and CHr in dogs between the ILE-affected and the healthy groups. Considerable variability among studies indicates caution in generalizing findings and makes conclusions less definitive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.