Evidence map›Paper›PMID 40911266›Full record

ArticleRadiological physics and technology2025

Classification of liver lesions based on temporal changes in hepatobiliary phase contrast on magnetic resonance imaging: a preliminary study.

Yasuo Takatsu, Masafumi Nakamura, Tomoko Tateyama, Tosiaki Miyati, Satoshi Kobayashi

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Article in Radiological physics and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yasuo TakatsuDepartment of Molecular Imaging, Clinical Collaboration Unit, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan. pcblue2@yahoo.co.jp.ORCID http://orcid.org/0000-0002-4384-089X
Masafumi NakamuraDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.
Tomoko TateyamaComputer Science and Intelligent System Program, Faculty of Engineering, University of the Ryukyus, 1 Senbaru, Nishihara-cho, Nakagami-gun, Okinawa, Japan.
Tosiaki MiyatiDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.
Satoshi KobayashiDivision of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated whether temporal changes from the dynamic late phase to the hepatobiliary phase using gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid supported liver tumor classification. A total of 147 patients with 165 lesions (hepatocellular carcinoma [HCC], metastases, and hemangiomas) underwent 3.0 T MRI. Quantitative liver lesion contrast (Q-LLC) and its rate of change (%) at 3, 10, and 15 min postcontrast were analyzed. Tumors were stratified according to albumin-bilirubin (ALBI) grade. For ALBI grade 1, the Q-LLC significantly differed at 3 min and 10 min (P < 0.05). Q-LLC increased over time, and the rate of change was the lowest in HCC, followed by metastases, and was the highest in hemangiomas. Significant differences in the rate of change were observed among tumor types for ALBI grade 1 (P < 0.01). These findings suggest that the Q-LLC rate of change may aid in liver tumor classification, particularly in patients with preserved liver function.

Indexed as

Biliary TractLiverLiver NeoplasmsMagnetic Resonance ImagingAdultAgedAged, 80 and overCarcinoma, HepatocellularContrast MediaFemaleGadolinium DTPAHumansMaleMiddle AgedTime FactorsContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPAGd-EOB-DTPALiver lesion classificationMagnetic resonance imagingQuantitative liver lesion contrast

Identifiers

PMID40911266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.