Evidence map›Paper›PMID 40911181›Full record

ArticleCurrent medical science2025

The Regulatory Mechanism of MicroRNA-144-3p on Damage to Endometrial Epithelial Cells Exposed to Copper Ions In Vitro.

Xiao-Rong Fan, Hou-Ze Zhu, Meng-Ying Lei, Peng-Jun Jiang, Hui Zhou, Wei Xia

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Article in Current medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiao-Rong FanMaternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, China.
Hou-Ze ZhuDepartment of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Meng-Ying LeiInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Peng-Jun JiangInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Hui ZhouInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. huizhousky@whu.edu.cn.ORCID http://orcid.org/0000-0001-8429-6213
Wei XiaInstitute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. tjxiawei@hust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the differential expression of microRNA-144-3p in endometrial cells exposed to copper ions in vitro. The specific mechanism by which microRNA-144-3p is involved in Cu

methodsHEECs were cultured in copper-containing culture medium to simulate changes in the endometrium after copper intrauterine device (Cu-IUD) implantation. Reverse transcription quantitative PCR (RT-qPCR) was used to detect the differential expression of miR-144-3p in HEECs after Cu

resultsMiR-144-3p was significantly upregulated in the Cu

conclusionsThe increased Cu

Indexed as

CopperEndometriumEpithelial CellsMicroRNAsCells, CulturedFemaleGene Expression RegulationHumansMatrix Metalloproteinase 9MetallothioneinNF-kappa BSignal TransductionSmad3 ProteinThrombospondin 1CopperMatrix Metalloproteinase 9MetallothioneinMicroRNAsMIRN144 microRNA, humanMMP9 protein, humanNF-kappa BSmad3 ProteinSMAD3 protein, humanThrombospondin 1Copper ionHuman endometrial epithelial cellMatrix metalloproteinaseMicroRNA-144-3pTranscription growth factor

Identifiers

PMID40911181

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.