Evidence map›Paper›PMID 40911177›Full record

ArticleInternational urology and nephrology2026

Finerenone in type 1 diabetes and chronic kidney disease: short-term efficacy and safety insights.

Dandan Qiu, Jingjing Wang, Aijuan Li, Wei Zhang, Xiaofeng Du, Genwang Wang, Song Jiang

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Dandan QiuNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China.
Jingjing WangNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China.
Aijuan LiNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China.
Wei ZhangNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China.
Xiaofeng DuNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China.
Genwang WangJinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Song JiangNational Clinical Research Center for Kidney Diseases, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Xuanwu District, No. 305 East Zhongshan Road, Nanjing, 210016, Jiangsu, China. js1120@163.com.

Funding

Clinical Diagnosis and Treatment New Technology Programs of Jinling Hospital 2023LCZLXA037National Key R&D Program of China 2020YFA0710800National Natural Science Foundation 82370733
6 · The paper itself

Abstract

purposeTo evaluate the short-term efficacy and safety of finerenone in patients with type 1 diabetes (T1D) and chronic kidney disease (CKD).

methodsA retrospective cohort study was conducted on a relatively small sample of 23 patients diagnosed with T1D and CKD between January 2023 and August 2024. All patients received renin-angiotensin system inhibitors (RASi), with 12 patients additionally treated with finerenone.

resultsThe cohort had a median age of 34 (29, 39) years, including 11 females. Median Hemoglobin A1c (HbA1c) was 7.30% (6.55, 8.10%), proteinuria was 1.49 (0.88, 2.84) g/24h, mean estimated glomerular filtration rate (eGFR) was 71.91 ± 24.59 mL/min/1.73m

conclusionIn this preliminary study, finerenone showed potential for attenuating kidney function decline in patients with T1D and CKD, though its long-term efficacy and safety require validation in larger trials.

Indexed as

Diabetes Mellitus, Type 1Diabetic NephropathiesMineralocorticoid Receptor AntagonistsNaphthyridinesRenal Insufficiency, ChronicAdultCohort StudiesFemaleHumansMaleRetrospective StudiesTime FactorsTreatment OutcomefinerenoneMineralocorticoid Receptor AntagonistsNaphthyridinesChronic kidney diseaseEfficacyFinerenoneType 1 diabetes

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.