Evidence map›Paper›PMID 40911126›Full record

ArticleDigestive diseases and sciences2026

Predictors for Achieving Textbook Outcomes After Endoscopic Resection of Giant Submucosal Tumors in the Esophagus and Cardia.

Wei Su, Yun Wang, Haihan Xu, Ji-Yuan Zhang, Xi-Guo Fang, Hao Hu, Quan-Lin Li, Yun-Shi Zhong, Yi-Qun Zhang, Wei-Feng Chen and 2 more

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Wei Su *Zhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Yun Wang *Zhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Haihan Xu *Gastroenterology Department, People's Hospital of Yian Dinstrict, Tonglin, Anhui, China.
Ji-Yuan Zhang *Zhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Xi-Guo FangGastroenterology Department, People's Hospital of Yian Dinstrict, Tonglin, Anhui, China.
Hao HuZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Quan-Lin LiZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Yun-Shi ZhongZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Yi-Qun ZhangZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Wei-Feng ChenZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Ping-Hong ZhouZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China. zhou.pinghong@zs-hospital.sh.cn.
Sheng-Li LinZhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China. zshenrylsl@163.com.

Funding

Major Project of Shanghai Municipal Science and Technology Committee 23ZR1445500Outstanding Youth Foundation of Zhongshan Hospital, Fudan University 202ZSYQ12the National Natural Science Foundation of China 8200062Yangfan program of Shanghai Municipal Science and Technology Committee 21YF1440100
6 · The paper itself

Abstract

BACKGROUND AND

aimsEndoscopic resection for submucosal tumors (SMTs) in the esophagus and cardia is challenging with hazards of adverse events and the exploration of its achieving textbook outcome (TO) was unknown. We aim to investigate the predictors of TO for giant SMTs with a long diameter ≥ 7 cm or a transverse diameter ≥ 3.5 cm.

methodsA retrospective review was conducted for endoscopic resection of consecutive patients with giant SMTs in the esophagus and cardia between July 2017 and February 2022 at the Endoscopy center of Zhongshan Hospital, Fudan University. TO was mainly defined as absences of major adverse events, piecemeal resection, and prolonged hospital stay. Clinicopathologic, procedural characteristics, adverse events, and follow-up outcomes were analyzed.

resultsA total of 109 patients who completed endoscopic resection were analyzed. The median long and transverse diameter of the tumors were 7.5 cm (range, 4-15 cm) and 4 cm (range, 1.5-7 cm), respectively. The en bloc resection rate was 78.9%. Transverse diameter < 4.5 cm and regular shape were independent predictors for TO. Major adverse events (mAEs) occurred in 14 patients (12.8%). Long diameter ≥ 9 cm and piecemeal resection were significantly associated with mAEs. During a median follow-up of 33.5 months, there was no tumor recurrence or metastasis.

conclusionGiant esophageal or cardia SMTs with a long diameter < 9 cm and transverse diameter < 4.5 cm indicated a safe and credible outcome for endoscopic resection.

Indexed as

CardiaEFTREsophagusGiant submucosal tumorsSTER

Identifiers

PMID40911126

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