Evidence map›Paper›PMID 40911080›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2026

Sentinel node detection and imaging concordance in Early-Stage ovarian cancer: A MELISA trial analysis of tracer, timing, and intraoperative gamma camera.

Nuria Agusti, Pilar Paredes, Sergi Vidal-Sicart, Federico Migliorelli, Cristina Celada, Nuria Carreras, Francisco Campos, Tiermes Marina, Inmaculada Romero, Ariel Glickman and 5 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nuclear medicine in the operating room: present and future.The British journal of radiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nuria AgustiDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. nagustiga@gmail.com.ORCID 0000-0002-1165-0661
Pilar ParedesDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Sergi Vidal-SicartDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Federico MigliorelliGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Cristina CeladaGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Nuria CarrerasGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Francisco CamposDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Tiermes MarinaGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Inmaculada RomeroDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Ariel GlickmanGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Andrea FritschDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Nahir NavarroDepartment of Nuclear Medicine, Hospital Clínic de Barcelona, Barcelona, Spain.
Pere FusteGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Aureli TorneGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.
Berta Diaz-FeijooGynecologic Oncology Department, Clinic Hospital, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the detection rate of sentinel lymph node (SLN) mapping in early-stage ovarian cancer using [

methodsThis was a prospective single-center trial of 63 patients with suspected early-stage epithelial ovarian cancer who underwent SLN mapping with combined tracers. [

resultsAmong 63 patients, sentinel lymph nodes (SLNs) were detected in 79.4% using [

conclusionSLN mapping in ovarian cancer using a dual tracer approach is feasible and yields a higher detection rate than single tracers. The gamma camera identified SLN localization mainly in aortic regions. This combination may improve nodal staging in early ovarian cancer and reduce the need for systematic lymphadenectomy. Post-adnexectomy injection is a practical alternative to injection before adnexectomy for immediate surgeries, although caution is needed due to potential variations in lymphatic drainage.

Indexed as

Gamma CamerasOvarian NeoplasmsSentinel Lymph NodeAdultAgedAged, 80 and overFemaleHumansIndocyanine GreenIntraoperative PeriodMiddle AgedNeoplasm StagingProspective StudiesRadioactive TracersSentinel Lymph Node BiopsyTechnetium Tc 99m Aggregated AlbuminIndocyanine GreenRadioactive TracersTechnetium Tc 99m Aggregated Albumintechnetium Tc 99m nanocolloidIndocyanine greenOvarian cancerRadioactive tracerSentinel lymph node

Identifiers

PMID40911080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.