Evidence map›Paper›PMID 40910883›Full record

ArticleRadiology. Imaging cancer2025

Evaluating Breast Cancer Intravoxel Incoherent Motion MRI Biomarkers across Software Platforms.

Eric E Sigmund, Gene Y Cho, Dibash Basukala, Olivia M Sutton, Joao V Horvat, Artem Mikheev, Henry Rusinek, Nima Gilani, Xiaochun Li, James S Babb and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Radiology. Imaging cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Eric E SigmundCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.ORCID 0000-0001-6783-3611
Gene Y ChoCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.
Dibash BasukalaCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.
Olivia M SuttonDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Joao V HorvatDepartment of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Artem MikheevCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.
Henry RusinekCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.ORCID 0000-0001-6035-6314
Nima GilaniCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.ORCID 0000-0002-6129-7763
Xiaochun LiDepartment of Population Health, New York University Grossman School of Medicine, New York, NY.ORCID 0000-0003-1109-6119
James S BabbCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.ORCID 0000-0003-1798-1186
Judith D GoldbergDepartment of Population Health, New York University Grossman School of Medicine, New York, NY.
Katja PinkerDepartment of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-2722-7331
Linda MoyCenter for Biomedical Imaging, Center for Advanced Innovation and Imaging Research (CAIIR), Department of Radiology, NYU Langone Health, 660 1st Ave, New York, NY 10016.ORCID 0000-0001-9564-9360
Sunitha B ThakurDepartment of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-8090-3696

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3M
Abbreviated Non-Contrast-Enhanced MRI for Breast Cancer ScreeningR01CA249893 · NCI · STANFORD UNIVERSITY · PI DANIEL, BRUCE L, HARGREAVES, BRIAN ANDREW · 2021 to 2025
$3.1M
MRI Radiomic Signatures of DCIS to Optimize TreatmentR01CA268341 · NCI · UNIVERSITY OF WASHINGTON · PI Despina Kontos, HABIBOLLAH RAHBAR · 2022 to 2026
$2.8M
Deciphering the Acidic Tumor Environment: A Phase I/IIa Study of Pre-Operative Multiparametric MRI and pHLIP® ICG Intra-Operative Fluorescence Imaging of Primary Breast CancerR01CA270018 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI MORROW, MONICA · 2023 to 2025
$2.0M
Breast Cancer Intravoxel-incoherent-motion MRI Multisite (BRIMM) Study - Resubmission - 1UH3CA239861 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SIGMUND, ERIC EDWARD, THAKUR, SUNITHA BAI · 2023 to 2025
$1.6M
Breast Cancer Intravoxel-incoherent-motion MRI Multisite (BRIMM) Study - Resubmission - 1UG3CA239861 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SIGMUND, ERIC EDWARD, THAKUR, SUNITHA BAI · 2021 to 2022
$771k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA249893NCI NIH HHS R01 CA268341NCI NIH HHS R01 CA270018NCI NIH HHS UG3 CA239861NCI NIH HHS UH3 CA239861NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Purpose To evaluate intravoxel incoherent motion (IVIM) biomarkers across different MRI vendors and software programs for breast cancer characterization in a two-site study. Materials and Methods This institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study included 106 patients (with 18 benign and 88 malignant lesions) who underwent bilateral diffusion-weighted imaging (DWI) between February 2009 and March 2013. DWI was performed using 1.5-T (

Indexed as

Breast NeoplasmsDiffusion Magnetic Resonance ImagingImage Interpretation, Computer-AssistedSoftwareAdultAgedFemaleHumansMiddle AgedRetrospective StudiesBreastMR-Diffusion Weighted ImagingTechnology Assessment

Identifiers

PMID40910883
PMCPMC12492437

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.