ArticleMicrobiology spectrum2025
HBV-encoded circRNA-5 promotes hepatocellular carcinoma progression by regulating the miR-9-3p/Hippo signaling axis.
Yong Yang, Yongshi Shen, Yuan Dang, Jingyun Huang, Yinghua Su, Jialiang Zhang, Xin Jiang, Xinying Luo, Jianmin Wang, Jingfeng Liu
Abstract read
In one paragraphArticle in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Yong Yang *Innovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.ORCID 0009-0003-6586-6331 Yongshi Shen *Department of Intensive Care Unit, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Yuan DangInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Jingyun HuangInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.ORCID 0009-0000-5768-9441 Yinghua SuCollege of Biological Science and Engineering, Fuzhou University, Fujian, China.
Jialiang ZhangInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Xin JiangInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Xinying LuoInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.
Jianmin WangInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.ORCID 0000-0002-7395-3270 Jingfeng LiuInnovation Center for Cancer Research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, China.ORCID 0000-0003-3499-5678 Funding
Fujian Medical University 2022QH1164Joint fund for the innovation of science and technology of fujian province 2021Y9197Natural Science Foundation of Fujian Province 2021J01445Natural Science Foundation of Fujian Province 2023J011262School management project of fujian university of traditional chinese medicine XB2023185the major science research program for young and middle-aged health professionals of Fujian province 2021ZQNZD009
6 · The paper itselfAbstract
Chronic hepatitis B virus (HBV) infection is regarded as one of the most serious infectious diseases and a significant global public health concern. Although the neonatal vaccine has been effective in impeding the transmission of HBV, tens of millions of HBV patients are still vulnerable to liver disease and even hepatocellular carcinoma (HCC). In this research, we demonstrated that HBV-encoded circRNA, designated as HBV-circRNA-5, was involved in the tumorigenesis of HCC. Overexpression of HBV-circRNA-5 promoted HCC cell proliferation and metastasis
Indexed as
Carcinoma, HepatocellularHepatitis B virusLiver NeoplasmsMicroRNAsRNA, CircularAnimalsCell Line, TumorCell ProliferationDisease ProgressionGene Expression Regulation, NeoplasticHepatitis B, ChronicHippo Signaling PathwayHumansMaleMiceMice, Inbred BALB CMicroRNAsMIRN92 microRNA, humanRNA, Circularchronic hepatitis B virusHBV-circRNA-5hepatocellular carcinoma
Identifiers
PMID40910771
PMCPMC12502530
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