Evidence map›Paper›PMID 40910688›Full record

ArticleJournal of virology2025

Hepatitis C virus modified

Yuki Haga, Preedia Babu E, Marzena Swiderska-Syn, Erin K Reagan, Drew Weissman, Ranjit Ray

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuki HagaDepartment of Internal Medicine, Saint Louis University, St. Louis, Missouri, USA.
Preedia Babu EDepartment of Internal Medicine, Saint Louis University, St. Louis, Missouri, USA.
Marzena Swiderska-SynDepartment of Paediatrics, Saint Louis University, St. Louis, Missouri, USA.
Erin K ReaganDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Drew WeissmanDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-1501-6510
Ranjit RayDepartment of Internal Medicine, Saint Louis University, St. Louis, Missouri, USA.ORCID 0000-0001-8813-3446

Funding

Nucleoside modified mRNA based HIV vaccineR01AI124429 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WEISSMAN, DREW · 2016 to 2019
$3.4M
SELECTION OF VACCINE ANTIGENS FOR PROTECTION FROM HEPATITIS C VIRUS INFECTIONR01DK122401 · NIDDK · SAINT LOUIS UNIVERSITY · PI RAY, RANJIT · 2020 to 2024
$1.7M
NIAID NIH HHS R01 AI124429NIDDK NIH HHS R01 DK122401
6 · The paper itself

Abstract

T cells play an important role in initiating antibody responses by instructive signals of cell-cell contacts and secretion of soluble cytokines as mediators. We investigated the role of the modified soluble E2 (sE2

Indexed as

HepacivirusHepatitis CReceptors, CXCR5Th17 CellsViral Hepatitis VaccinesAnimalsFemaleHumansInterleukin-17Leukocytes, MononuclearLiposomesMiceNanoparticlesRNA, MessengerT-Lymphocytes, Helper-InducerViral Envelope Proteinsglycoprotein E2, Hepatitis C virusInterleukin-17Lipid NanoparticlesLiposomesReceptors, CXCR5RNA, MessengerViral Envelope ProteinsViral Hepatitis VaccinesDCsfollicular B helper T cellsHCVNK cellssE2sE2F442NYTTh17 cells

Identifiers

PMID40910688
PMCPMC12548457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.