Evidence map›Paper›PMID 40910687›Full record

ArticleJournal of virology2025

Molnupiravir inhibits Bourbon virus infection and disease-associated pathology in mice.

Gayan Bamunuarachchi, Fang R Zhao, Traci L Bricker, Kuljeet Seehra, Andrew Karp, Michael S Diamond, Adrianus C M Boon

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gayan BamunuarachchiDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0001-5233-772X
Fang R ZhaoDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Traci L BrickerDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Kuljeet SeehraDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Andrew KarpDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Michael S DiamondDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Adrianus C M BoonDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-4700-8224

Funding

Emerging infections: surveillance, epidemiology and pathogenesisU01AI151810 · NIAID · WASHINGTON UNIVERSITY · PI Adrianus CM Boon, DAVID WANG · 2020 to 2026
$10.0M
Mechanism and Inhibition of Thogotovirus EntryR01AI173327 · NIAID · WASHINGTON UNIVERSITY · PI Adrianus CM Boon, Daved H. Fremont · 2023 to 2026
$2.8M
Bourbon virus: Therapy development and SerologyR21AI151170 · NIAID · WASHINGTON UNIVERSITY · PI BOON, ADRIANUS CM · 2020 to 2021
$433k
NIAID NIH HHS R01 AI173327NIAID NIH HHS R21 AI151170NIAID NIH HHS U01 AI151810
6 · The paper itself

Abstract

Bourbon virus (BRBV) is an emerging tick-borne virus that can cause severe and fatal disease in humans. BRBV is vectored via the

Indexed as

Antiviral AgentsCytidineHydroxylaminesRNA Virus InfectionsTick-Borne DiseasesAnimalsDisease Models, AnimalFemaleHumansMiceMice, Inbred C57BLMice, KnockoutVirus ReplicationAntiviral AgentsCytidineHydroxylaminesmolnupiravirantiviralBourbon viruscytopeniaDhori virusmolnupiravirpathologypre-clinical modelThogoto virustick-borne disease

Identifiers

PMID40910687
PMCPMC12548437

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.