Evidence map›Paper›PMID 40910574›Full record

ArticleOrganic letters2025

Approach to Heterospirocycles for Medicinal Chemistry.

Carlos Rodríguez-Arias, Rubén Miguélez, Yuliia Holota, Pavel K Mykhailiuk, Pablo Barrio

Abstract read
In one paragraph

Article in Organic letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos Rodríguez-AriasDepartamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, Julian Clavería 8, 33006 Oviedo, Spain.
Rubén MiguélezDepartamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, Julian Clavería 8, 33006 Oviedo, Spain.
Yuliia HolotaEnamine, Limited, Chervonotkatska 78, 02094 Kyiv, Ukraine.
Pavel K MykhailiukEnamine, Limited, Chervonotkatska 78, 02094 Kyiv, Ukraine.ORCID 0000-0003-1821-9011
Pablo BarrioDepartamento de Química Orgánica e Inorgánica and Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, Julian Clavería 8, 33006 Oviedo, Spain.ORCID 0000-0001-7101-4037

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gold(I)-catalyzed cycloisomerization of aliphatic 1-bromoalkynes has been applied to the synthesis of heterospirocycles. The reactivity of the C(sp

Identifiers

PMID40910574
PMCPMC12455649

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.