Evidence map›Paper›PMID 40910333›Full record

ArticleThe Canadian journal of urology2025

Tumor-to-tumor metastasis: case report of a neuroendocrine tumor of the lung metastasizing to a benign oncocytoma of the kidney.

Siddharth Marthi, Muhammad Mukarram, Fatemeh Ardeshir-Larijani, Lara Rabih Harik, Shreyas Subhash Joshi

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In one paragraph

Article in The Canadian journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siddharth MarthiDepartment of Urology, Emory University, Atlanta, GA 30322, USA.
Muhammad MukarramDepartment of Urology, Emory University, Atlanta, GA 30322, USA.
Fatemeh Ardeshir-LarijaniWinship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
Lara Rabih HarikDepartment of Pathology, Emory University, Atlanta, GA 30322, USA.
Shreyas Subhash JoshiDepartment of Urology, Emory University, Atlanta, GA 30322, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-to-tumor metastasis (TTM) is a rare phenomenon in which a secondary tumor colonizes within a primary tumor of a different histogenesis. It is hypothesized that TTM is encouraged by conditions that promote increased cell growth and division in the primary tumor, such as hypervascularity and expression of oncogenic cytokines. However, the exact causes of TTM likely vary on a case-by-case basis and are dependent on the microenvironment of both the primary and secondary tumors. Herein, we present the first reported example of TTM in which a pulmonary neuroendocrine tumor (NET) metastasizes to a renal oncocytoma.

Indexed as

Adenoma, OxyphilicKidney NeoplasmsLung NeoplasmsNeuroendocrine TumorsHumansMaleMiddle Agedcase reportneuroendocrine tumoroncocytomatumor-to-tumor metastasis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.