Evidence map›Paper›PMID 40910244›Full record

ReviewCurrent diabetes reviews2026

Mapping the Landscape of Epigenetic Research in Diabetes Mellitus: A Decade-Long Bibliometric Analysis (2014-2024).

Yu'e Tang, Huan Zhu, Lele Liu, Xiuying Guo, Qianbo Zhang, Yuhe Dai, Junqi Yang, Rifang Gu, Jidong Rong, Xuqiang Nie

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu'e TangSchool of Clinical Medicine, Zunyi Medical University, Zunyi, 563006, China.
Huan ZhuCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Lele LiuCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Xiuying GuoCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Qianbo ZhangCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Yuhe DaiCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Junqi YangCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.
Rifang GuSchool Medical Office, Zunyi Medical University, Zunyi, 563006, China.
Jidong RongDepartment of Cardiology, The Affiliated Hospital of Zunyi Medical University, Zunyi, 563006, China.
Xuqiang NieCollege of Pharmacy, Zunyi Medical University, Zunyi, 563006, China.

Funding

Health Commission of Guizhou Province gzwkj2023-298National College Students Innovation and Entrepreneurship Training Program S202310661096National Natural Science Foundation of China 82160770, 82460792Outstanding Young Scientific and Technological Talents Project of Guizhou Province 2021-5639Scientific and Technological Innovation Talent Team of Guizhou Province CXTD [2023] 024Zunyi Science and Technology Talent Platform Carrier Construction Project ZSKRPT2023-1
6 · The paper itself

Abstract

introductionEpigenetic regulation constitutes critical molecular mechanisms underlying the pathogenesis of diabetes and disease progression. While substantial mechanistic investigations exist, the field lacks systematic mapping of research trends, collaborative networks, and emerging frontiers.

objectivesTo conduct the first comprehensive bibliometric evaluation of epigenetic studies in diabetes mellitus and its complications (2014-2024), identifying key research domains, international collaboration patterns, and innovative investigative directions to inform strategic research planning and highlight opportunities for innovative therapeutic approaches.

methodsWe interrogated the Web of Science Core Collection using stringent inclusion criteria, analyzing 1,451 publications through advanced multi-dimensional metrics in CiteSpace (6.2.R4), VOSviewer (1.6.20), and Bibliometrix (4.1.3). RESULTS AND DISCUSSION: A total of 1,451 original and review articles were retrieved, involving 83 countries/regions, 576 journals, and 7,645 authors. The United States produced the highest number of publications (n = 464), followed by China (n = 283) and Italy (n = 121). The International Journal of Molecular Sciences was the leading journal (66 publications), dominated by review articles (n = 53). Author collaboration networks were extensive, with Charlotte Ling emerging as the most prolific and influential author in publications, citations, and H-index. Keyword co-occurrence analyses emphasized type 2 DM, gestational DM, and diabetic nephropathy as primary research focuses, while new frontiers highlighted potential links to Alzheimer's disease and fibroblast biology.

conclusionThis multi-dimensional analysis provides quantitative visualization of research evolution, delineates current investigative priorities, and highlights underexplored therapeutic targets. Our findings establish a strategic framework for transdisciplinary collaboration in precision diabetology.

Indexed as

BibliometricsBiomedical ResearchDiabetes MellitusEpigenesis, GeneticEpigenomicsHumanschronic hyperglycemiacollaboration networksDNA methylationhistone modificationMolecular pathologyresearch mapping

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.