ArticleFrontiers in oncology2025
Primary vulval sebaceous carcinoma: rare case report and literature review.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
This study presents a rare case of primary vulval sebaceous carcinoma (SC) and a literature review. Sebaceous carcinoma is an aggressive skin malignancy, predominantly periocular, with extraocular cases being particularly uncommon. We detail a 50-year-old female patient diagnosed with primary vulval SC, exhibiting a 0.5 cm white lesion on her left vulva. Despite initial drug therapy, the lesion progressed to ulceration and induration. Histopathological examination confirmed SC. The patient underwent extensive local vulvectomy and sentinel lymph node biopsy, showing no evidence of metastasis. At 22 months post-surgery, the patient remained recurrence-free. A literature review identified 13 additional cases, highlighting diverse presentations and management strategies. Our findings underscore the importance of sentinel lymph node biopsy and tailored surgical approaches for early-stage disease. The study contributes to the understanding of this rare condition and may inform future management protocols.
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