Evidence map›Paper›PMID 40909791›Full record

ArticleResearch square2025

New genetic tools for central and peripheral vascular endothelia.

Shangzhou Xia, Tenghuan Ge, Ruocen Song, Qinghai Liu, Xiao He, Yvonne Shen, Haowen Qiao, Yafei Qu, Jian-Fu Chen, Zhen Zhao and 1 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shangzhou XiaUniversity of Southern California.
Tenghuan GeUniversity of Southern California.
Ruocen SongUniversity of Southern California.
Qinghai LiuUniversity of Southern California.
Xiao HeUniversity of Southern California.
Yvonne ShenUniversity of Southern California.
Haowen QiaoUniversity of Southern California.
Yafei QuUniversity of Southern California.
Jian-Fu ChenUniversity of Southern California.
Zhen ZhaoUniversity of Southern California.
Xinying GuoGuangzhou Women and Children's Medical Center, Guangzhou Medical University.

Funding

The role of ATP13A5 ATPase in determining blood-brain pericyte functionsRF1NS135617 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2023 to 2023
$2.4M
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseRF1NS122060 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2021 to 2021
$2.3M
Pericyte-neuronal crosstalk in health and Alzheimer's DiseaseR01AG061288 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2019 to 2023
$2.1M
Probing the heterogeneity of brain pericytes using new genetic toolsR21AG085559 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2024 to 2025
$456k
NIA NIH HHS R01 AG061288NIA NIH HHS R21 AG085559NINDS NIH HHS RF1 NS122060NINDS NIH HHS RF1 NS135617
6 · The paper itself

Abstract

The divergence between the central and peripheral vascular system, particularly the emergence of the blood-brain barrier (BBB), is central to the brain's homeostasis and functions. However, the molecular and genetic constituents that separating the BBB vascular cells from the rest remain elusive. Using single cell transcriptomics, we identified new cerebrovascular markers, e.g. zinc finger protein

Identifiers

PMID40909791
PMCPMC12408035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.